A critical review of the physiological importance and analysis of sperm movement in mammals
TLDR
A critical review of a number of aspects of hyperactivated motility, including its identification and potential role(s) in mammalian fertilization, is presented.Abstract:
The identification of human sperm hyperactivated motility has potential importance in sperm function tests, as well as in quality control assays and in reproductive toxicology investigations. However, relatively little is known about this phenomenon and the variety of definitions used for hyperactivation has led to a great deal of confusion as to its occurrence and physiological relevance. This presentation is a critical review of a number of aspects of hyperactivated motility, including its identification and potential role(s) in mammalian fertilization. The initial sections of the review consider the mechanisms involved in the development and maintenance of mammalian sperm motility, and the structural and functional changes in spermatozoa which occur during transport through the female reproductive tract. The methods available for the quantification of aspects of sperm movement are also discussed, with an historical overview of sperm movement analysis.read more
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Computer assisted semen analyzers in andrology research and veterinary practice
TL;DR: Although some interesting results, mainly in humans, have already been obtained, many questions remain, which have to be answered to allow for further development of this technology in veterinary medicine, clinical fertility settings, physiological and toxicology research activities.
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Control of hyperactivation in sperm
TL;DR: Computer-assisted semen analysis systems can be used to identify hyperactivated sperm by setting minimum thresholds for curvilinear velocity and lateral head movement and a maximum threshold for path linearity, which could enable clinicians to develop reliable fertility assays to assess normal hyperactivation in human sperm samples.
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Male infertility, impaired sperm motility, and hydrocephalus in mice deficient in sperm-associated antigen 6.
Rossana Sapiro,Igor Kostetskii,Patricia Olds-Clarke,George L. Gerton,Glenn L. Radice,Jerome F. Strauss +5 more
TL;DR: It is concluded that Spag6 is essential for sperm flagellar motility and that it is important for the maintenance of the structural integrity of mature sperm.
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Effects that bovine sperm cryopreservation using two different extenders has on sperm membranes and chromatin.
Eneiva Carla Carvalho Celeghini,Rubens Paes de Arruda,André Furugen Cesar de Andrade,Juliana Nascimento,Cláudia Fernandes Raphael,Paulo Henrique Mazza Rodrigues +5 more
TL;DR: The Botu-Bov extender was more effective in preserving sperm motility and membrane integrity than was the Bioxcell extender, and the integrity of plasma membranes, acrosomal membranes and chromatin was evaluated using the acridine orange technique.
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Male infertility caused by spermiogenic defects: lessons from gene knockouts.
TL;DR: The mouse studies strongly suggest that sperm quality rather than quantity is a better indicator of male fertility and novel assays should be developed to determine sperm functionality.
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TL;DR: This book is a blend of erudition, popularization, and exposition, and the illustrations include many superb examples of computer graphics that are works of art in their own right.
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