Journal ArticleDOI
Acquisition of Serum Antibody to Norwalk Virus and Rotavirus and Relation to Diarrhea in a Longitudinal Study of Young Children in Rural Bangladesh
TLDR
Serum antibodies to Norwalk virus and to rotavirus were measured during longitudinal studies of infectious diseases and nutrition in rural Bangladesh to find children with the lowest levels of antibody to rotvirus had the greatest risk of rotav virus diarrhea.Abstract:
Serum antibodies to Norwalk virus and to rotavirus were measured during longitudinal studies of infectious diseases and nutrition in rural Bangladesh. Initially, the prevalence of antibody to Norwalk virus was 7% in children younger than six months and increased to 80% in children two to five years of age. The incidence of titer increases was highest in one- and two-year-olds and in children who had low or undetectable levels of antibody. Some Norwalk virus infections appeared to result in diarrhea. Nearly all children had serum antibodies to rotavirus at the beginning of the study; however, children with the lowest levels of antibody to rotavirus had the greatest risk of rotavirus diarrhea. Over half of the children had a fourfold increase in titer of antibody to rotavirus during the year, and 7% had increases in two of the three study periods during the year. Most increases in titer of antibody to rotavirus appeared to result from subclinical infections.read more
Citations
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Journal ArticleDOI
Clinical immunity after neonatal rotavirus infection. A prospective longitudinal study in young children.
TL;DR: It is concluded that neonatal rotavirus infection does not confer immunity against reinfection but does protect against the development of clinically severe disease during reinfections.
Journal ArticleDOI
Case-Control Study of Enteropathogens Associated with Childhood Diarrhea in Dhaka, Bangladesh
TL;DR: This study studied 814 children with diarrhea in Bangladesh and identified rotavirus, Campylobacter jejuni, enterotoxigenic Escherichia coli, Shigella spp.
Journal ArticleDOI
Protection of infants against rotavirus diarrhoea by rit 4237 attenuated bovine rotavirus strain vaccine
TL;DR: Vaccine prepared from RIT 4237 strain of attenuated bovine rotavirus thus seems to protect children against heterologous subgroup 2 rotav virus diarrhoea.
Journal ArticleDOI
The epidemiology of enteric caliciviruses from humans: a reassessment using new diagnostics.
Roger I. Glass,Jacqueline S. Noel,Tamie Ando,Rebecca L. Fankhauser,Gaël Belliot,Anthony W. Mounts,Umesh D. Parashar,Joseph S. Bresee,Stephan S. Monroe +8 more
TL;DR: Novel molecular methods have permitted outbreak strains to be traced back to their common source and have led to the first identification of virus in implicated vehicles of infection-water, shellfish, and foods contaminated both at their source and by food handlers.
Journal ArticleDOI
Incidence and etiology of infantile diarrhea and major routes of transmission in huascar, peru
Robert E. Black,Guiller∼O Lopez De Roma,Kenneth H. Brown,Nora Bravo,Oscar Grados Bazalar,Hilary Creed Kanashtro +5 more
TL;DR: Improved feeding practices, along with avoidance of animal feces and improved personal and domestic hygiene, should be considered important interventions in reducing the high incidence of diarrhea in infants in developing countries.
References
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Journal ArticleDOI
Statistical Methods for Rates and Proportions.
B. S. Everitt,Joseph L. Fleiss +1 more
Book
Diagnostic Procedures for Viral, Rickettsial and Chlamydial Infections
TL;DR: This revised edition includes chapters on monoclonal antibodies, electron microscopy, nucleic acid probes, papovaviruses, parvoviruses and human retroviruses.
Journal ArticleDOI
Comparison of Three Agents of Acute Infectious Nonbacterial Gastroenteritis by Cross-Challenge in Volunteers
Richard G. Wyatt,Raphael Dolin,Neil R. Blacklow,Herbert L. DuPont,Robert F. Buscho,Thomas S. Thornhill,Albert Z. Kapikian,Robert M. Chanock +7 more
TL;DR: Volunteers were cross-challenged with bacteria-free stool filtrates derived from each outbreak of the Norwalk and Hawaii outbreaks to determine whether illness was produced by antigenically related or unrelated agents.
Journal ArticleDOI
A two-year study of bacterial, viral, and parasitic agents associated with diarrhea in rural Bangladesh
Robert E. Black,Robert E. Black,Robert E. Black,Michael H. Merson,Michael H. Merson,Michael H. Merson,A. S. M. M. Rahman,A. S. M. M. Rahman,A. S. M. M. Rahman,M. Yunus,M. Yunus,M. Yunus,A. R. M. A. Alim,A. R. M. A. Alim,A. R. M. A. Alim,I. Huq,I. Huq,I. Huq,Robert H. Yolken,Robert H. Yolken,Robert H. Yolken,G. T. Curlin,G. T. Curlin,G. T. Curlin +23 more
TL;DR: The low case-fatality rates for patients with watery diarrhea and substantial dehydration further document the usefulness of treating patients with diarrhea with either a glucose- or sucrose-base electrolyte solution such as those used in this treatment center.
Journal ArticleDOI
Longitudinal studies of infectious diseases and physical growth of children in rural Bangladesh: II. Incidence of diarrhea and association with known pathogens
TL;DR: Longitudinal studies were done in two villages rural Bangladesh to learn more about the interactions between infectious diseases and the nutritional status of children, and found E. coli diarrhea had a peak incidence during the hot months, and shigellosis was more frequent during the cool, dry months.