Adult Patients With Bronchiectasis: A First Look at the US Bronchiectasis Research Registry.
Timothy R. Aksamit,Anne E. O'Donnell,Alan F. Barker,Kenneth N. Olivier,Kevin L. Winthrop,M. Leigh Anne Daniels,Margaret M. Johnson,Edward Eden,David E. Griffith,Michael R. Knowles,Mark L. Metersky,Matthias Salathe,Byron Thomashow,Gregory Tino,Gerard M. Turino,Betsy Carretta,Charles L. Daley +16 more
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TLDR
Adult patients with bronchiectasis enrolled in the US BRR are described, with differences noted in demographic, radiographic, microbiological, and treatment variables based on stratification of the presence of NTM.About:
This article is published in Chest.The article was published on 2017-05-01 and is currently open access. It has received 243 citations till now. The article focuses on the topics: Bronchiectasis.read more
Citations
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Potency of omadacycline against Mycobacteroides abscessus clinical isolates in vitro and in a mouse model of pulmonary infection.
Danielle A. Nicklas,Emily C. Maggioncalda,Elizabeth Story-Roller,Benjamin Eichelman,Chavis Tabor,Alisa W Serio,Tiffany R. Keepers,Surya Chitra,Gyanu Lamichhane +8 more
TL;DR: Omadacycline was used to treat M. abscessus using in vitro and in vivo approaches as discussed by the authors, achieving an MIC90 of 0.5 μg/ml against a panel of 32 contemporary M.Abscessus clinical isolates.
Journal ArticleDOI
Management of bronchiectasis in adults.
TL;DR: The recent addition of a bronchiectasis diagnosis‐related group to the Australian Refined Diagnostic Related Group classification system will allow definition of the disease burden within the Australian hospital system.
Journal ArticleDOI
Management of nontuberculous mycobacterial pulmonary disease.
TL;DR: The evidence base for optimal management of NTM pulmonary disease is expanding but notable gaps in the literature remain.
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Paediatric and adult bronchiectasis: Diagnosis, disease burden and prognosis.
Jennifer K Quint,Maeve P. Smith +1 more
TL;DR: This review will discuss the diagnosis of bronchiectasis, the international burden of the disease and its current prognosis.
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Comorbidity before and after a diagnosis of inflammatory bowel disease.
TL;DR: In this paper, the authors used Cox proportional hazards regression to determine pre-diagnosis relative rates (RR) and postdiagnosis hazard ratios (HR) of component diseases of the Charlson Comorbidity Index (CCI) in a cohort study of persons with IBD.
References
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British Thoracic Society guideline for non-CF bronchiectasis.
TL;DR: These guidelines were designed to identify relevant studies in non-cystic fibrosis (CF) bronchiectasis, to provide guidelines on management based on published studies where possible or a consensus view, and to identify gaps in knowledge and identify areas for future study.
Journal ArticleDOI
An investigation into causative factors in patients with bronchiectasis
Mark C. Pasteur,Sharon M. Helliwell,Sally J. Houghton,Susannah C. Webb,J. Foweraker,Richard Coulden,Christopher D.R. Flower,Diana Bilton,Mary T. Keogan +8 more
TL;DR: Intensive investigation of this population of patients with bronchiectasis led to identification of one or more causative factor in 47% of cases, and the cause identified had implications for prognosis and treatment.
Journal ArticleDOI
Pulmonary Nontuberculous Mycobacterial Disease: Prospective Study of a Distinct Preexisting Syndrome
Richard D. Kim,David E. Greenberg,Mary Ehrmantraut,Shireen V. Guide,Li Ding,Yvonne R. Shea,Margaret R. Brown,Milica S. Chernick,Wendy K. Steagall,Connie G. Glasgow,JingPing Lin,Clara Jolley,Lynn Sorbara,Mark Raffeld,Suvimol Hill,Nilo A. Avila,Vandana Sachdev,Lisa A. Barnhart,Victoria L. Anderson,Reginald J. Claypool,Dianne Hilligoss,Mary Garofalo,Alan Fitzgerald,Sandra Anaya-O'Brien,Dirk Darnell,Rosamma DeCastro,Heather M. Menning,Stacy M. Ricklefs,Stephen F. Porcella,Kenneth N. Olivier,Joel Moss,Steven M. Holland +31 more
TL;DR: Patients with PNTM infection are taller and leaner than control subjects, with high rates of scoliosis, pectus excavatum, mitral valve prolapse, and cystic fibrosis transmembrane conductance regulator mutations, but without recognized immune defects.
Journal ArticleDOI
Prevalence and Economic Burden of Bronchiectasis
TL;DR: It is suggested that over 110,000 persons in the United States may be receiving treatment for bronchiectasis, resulting in additional medical-care expenditures of $630 million annually.
Journal ArticleDOI
Non–Cystic Fibrosis Bronchiectasis
TL;DR: A concise clinical review focuses on the major etiologies, diagnostic testing, microbiology, and management of patients with adult non-cystic fibrosis bronchiectasis, and outline current therapies and review the data that support their use.
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