Journal ArticleDOI
Algorithms for Adjustment of Insulin Dosage by Patients Who Monitor Blood Glucose
TLDR
An approach by which patient-determined blood glucose measurements may be used to attain and maintain glycemic control is described, provided with a set of algorithms by which minor adjustments in a therapeutic routine may be made to achieve the desired control.Abstract:
Patient self-monitoring of blood glucose is a useful adjuvant to diabetes therapy that facilitates improved glycemic control when used as part of an intensive diabetes management program that includes careful balancing of food intake, energy expenditure, and insulin dosage. This paper describes an approach by which patient-determined blood glucose measurements may be used to attain and maintain glycemic control. The patient is provided with a set of algorithms by which minor adjustments in a therapeutic routine may be made to achieve the desired control.read more
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Patent
External infusion device with remote programming, bolus estimator and/or vibration alarm capabilities
Alfred E. Mann,James D. Causey,Alan Haubach,Luis J. Malave,John H. Livingston,Hague Clifford W,Chad Srisathapat,Jay Yonemoto,Deborah Ruppert,Dennis P. Bishop,Adrian Gut,Murtfeldt Robert +11 more
TL;DR: In this paper, an infusion system for infusing a liquid into a body includes an external infusion device and a remote commander, which includes a commander housing, a keypad for transmitting commands.
Journal ArticleDOI
Monomeric insulins and their experimental and clinical implications.
TL;DR: The development of a series of human insulin analogues with reduced tendency to selfassociation that, because of more rapid absorption, are better suited to meal-related therapy and have the potential to minimize late hypoglycemia.
Journal ArticleDOI
A physiological model of glucose-insulin interaction in type 1 diabetes mellitus.
E.D. Lehmann,T. Deutsch +1 more
TL;DR: A clinical model of glucose-insulin interaction in insulin-dependent diabetes mellitus has been developed for patient and medical staff education and the possible use of the model as a tool for automated insulin dosage adjustment is explored.
Journal ArticleDOI
The effects of traditional antidiabetic plants on in vitro glucose diffusion
TL;DR: The results suggest that part of the antihyperglycemic actions of these plants may be by decreasing glucose absorption in vivo.
Journal ArticleDOI
Computer Simulation of Plasma Insulin and Glucose Dynamics After Subcutaneous Insulin Injection
Markus Berger,David Rodbard +1 more
TL;DR: A computer program that incorporates a pharmacokinetic model to calculate the time courses of plasma insulin for various combinations of popular preparations and can explore on a theoretical basis the impact of various factors associated with glycemic control in insulin-dependent diabetes mellitus.
References
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Journal ArticleDOI
In search of the somogyi effect
Journal ArticleDOI
Stimulation of counterregulatory hormonal responses in diabetic man by a fall in glucose concentration.
TL;DR: Results indicate that diabetic subjects with fasting hyperglycemia have an upward resetting of the glucostat at which counterregulatory hormones are released and provide direct support for the clinical observation of hypoglycemic reactions in some diabetics with “normal” or high plasma glucose concentrations.
Journal ArticleDOI
Home Blood Glucose Monitoring As an Aid in Diabetes Management
TL;DR: Home blood glucose monitoring, using Dextrostix and an Eyetone meter, has been utilized in several subcategories of patients with insulin-dependent diabetes mellitus, including pregnant patients, anephric patients, patients undergoing weight reduction, patients with altered renal threshold for glucose re absorption, and patients in whom diabetic regulation is difficult.
Journal ArticleDOI
Feasibility of Improved Blood Glucose Control in Patients With Insulin-Dependent Diabetes Mellitus
Charles M. Peterson,Robert L. Jones,Andre Dupuis,Barbara S Levine,Richard K Bernstein,Michael O'Shea +5 more
TL;DR: An outpatient program such as this may be cost effective through the avoidance of diabetes-related hospitalizations and may provide a mechanism whereby larger studies can be designed to define further the relationship of glycemia to the sequelae of diabetes.
Journal ArticleDOI
Patient self-monitoring of blood glucose and refinements of conventional insulin treatment.
TL;DR: Three times daily insulin injections with feedback from home blood-glucose monitoring give as good blood glucose control as infusion systems and are cheaper and more acceptable to patients.
Related Papers (5)
Computer-assisted insulin dosage adjustment.
Computer Simulation of Plasma Insulin and Glucose Dynamics After Subcutaneous Insulin Injection
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