David N. Finegold

TL;DR: It is found that isolated human primary lymphatic and blood vascular endothelial cells show interesting differences in gene expression relevant for their distinct functions in vivo, and overexpression of the homeobox transcription factor Prox‐1 in the BECs is suggested to act as a cell proliferation inducer and a fate determination factor for the LECs.

TL;DR: It is established that VEGFR-3 is important for normal lymphatic vascular function and that mutations interfering with VEGfr-3 signal transduction are a cause of primary lymphoedema.

TL;DR: By using virus-mediated VEGF-C gene therapy, the results suggest that growth factor gene therapy is applicable to human lymphedema and provide a paradigm for other diseases associated with mutant receptors.

TL;DR: The data show that Foxc2 is essential for the morphogenesis of lymphatic valves and the establishment of a pericyte-free lymphatic capillary network and that it cooperates with Vegfr3 in the latter process.

TL;DR: A carbohydrate sensing material, which consists of a crystalline colloidal array (CCA) incorporated into a polyacrylamide hydrogel with pendent boronic acid groups, which responds to species containing vicinal cis diols such as carbohydrates.