Showing papers in "The Lancet in 1980"

TL;DR: Disintergration of kidney stones by shock waves seems to be a promising form of treatment that reduces the need for surgery and can in many cases be done under epidural instead of general anaesthesia.

TL;DR: In the Whitehall Study of 18,403 male civil servants aged 40--64 years, 7 1/2 year coronary-heart-disease (CHD) mortality has been examined in relation to blood-sugar concentration 2 h after a 50 g oral glucose load, and age, systolic blood-pressure, and ECG abnormality were significantly predictive of subsequent CHD mortality.

TL;DR: Ten preterm infants severely ill with hyaline-membrane disease were given artificial surfactant endotracheally and eight survived, including five of six with birthweight less than 1500 g; two died of unrelated causes.

TL;DR: The generality of the advantage suggests that vigorous exercise is a natural defence of the body, with a protective effect on the ageing heart against ischaemia and its consequences.

TL;DR: 100 women who had taken part in a prospective controlled trial of oestrogen therapy for prevention of post-oophorectomy bone loss were reviewed after a median follow-up period of nine years.

TL;DR: The general epidemiology of factor VIIc, factor VIIIc, and fibrinogen is consistent with their having a role in the pathogenesis of IHD, and a clustering of two or three high clotting-factor values was present at recruitment in 63% of those who died of cardiovascular disease, compared with 23% ofThose who survived.

TL;DR: It is suggested that failure of fatty-acid (n-butyrate) oxidation in UC is an expression of an energy-deficiency disease of the colonic mucosa, especially the frequency of UC in the distal colon.

TL;DR: Women who had previously given birth to one or more infants with a neural-tube defect were recruited into a trial of periconceptional multivitamin supplementation and found no difference in the number of infants/fetuses with an NTD.

TL;DR: Eicosapentaenoic acid (C20:5 omega 3), which is present in high concentration in certain salt-water fish, may reduce the incidence of cardiovascular disease in Greenland Eskimos by reducing platelet aggregation and adhesion.

TL;DR: In this paper, the authors found that aggregation of polymorphonuclear granulocytes (PMN) in response to activated complement (C) might contribute to the genesis of the adult respiratory distress syndrome (ARDS), aggregating PMNs causing pulmonary dysfunction by becoming lodged in the lung as leucoemboli.

TL;DR: 69 serum pairs from two common-source water-borne outbreaks and one series of endemic cases of hepatitis in three parts of India were tested for hepatitis A and hepatitis B virus infections and none of the patients had evidence of HAV infection.

TL;DR: Two indices of alveolar epithelial permeability were derived in man by a non-invasive method and a significantly greater transfer rate was found in symptomless cigarette smokers compared with non-smokers.

TL;DR: In this article, the incidence of post-implantation pregnancy loss in 197 women was determined prospectively, based on the detection of human chorionic gonadotropin in the urine during the luteal phase of each menstrual cycle.

TL;DR: Intraventricular gentamicin should not be used as routine treatment for neonatal meningitis caused by gram-negative enteric bacilli, because of the higher mortality rate in the intraventricular-therapy group.

TL;DR: Clinical heterogeneity within the spinal muscular atrophies (SMA) has long been a source of confusion for questions of prognosis and genetic counselling but comprehensive clinical and genetic analyses of 240 consecutive index cases have enabled some nosological questions to be resolved.

TL;DR: Simple forms of analysis of perinatal mortality by birth weight and major pathological subgroup are suggested as ways for maternity hospitals and health authorities to initiate cost-effective improvements in perinnatal care.

TL;DR: In 23 hypertensive men, aged 47-55, propranolol reduced serum high-density-lipoprotein (HDL) cholesterol by 13% and prazosin reduced total serum cholesterol by 9%, LDL+VLDL cholesterol by 10%, and total triglycerides by 16%.

TL;DR: Several toxic effects of cyclosporin A have been observed but they are mostly reversible and no second malignant neoplasm has developed.

TL;DR: The results suggest that the analgesia observed after electroacupuncture in patients with recurrent pain may be mediated by the release into the CSF of the endogenous opiate, beta-endorphin.

TL;DR: The introduction of low-œstrogen oral contraceptives in Sweden and the concomitant disappearance of high-dose preparations did not result in a lowering of the mortality of fertile women from thromboembolic disease.

TL;DR: It was noted that the distribution of DR antigens in the hydralazine-SLE patients was significantly different from that in the group with idiopathic SLE, which supports the view that the syndromes are separate entities.

TL;DR: Modern diagnostic methods and routine estimations of serum calcium can be expected to yield at least 250 new cases of primary hyperparathyroidism per million population per year.