Journal ArticleDOI
Alterations in consummatory behavior of mice produced by dietary exposure to inorganic lead.
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The results indicate both learned and unlearned changes in motivation for fluid following ingestion of lead via the mother's milk in infancy.Abstract:
Mice suckled by mothers given tap water and by mothers given a 5 mg/ml lead acetate solution during lactation were given a choice between tap water and a lead acetate solution after lactation. All offspring demonstrated an immediate aversion to the lead acetate solution. The offspring from the mothers receiving lead acetate during lactation demonstrated a greater aversion to the lead acetate solution than did the offspring from mothers receiving tap water. In addition, the lead acetate offspring drank more total fluid (tap water plus lead acetate solution) after weaning than the control offspring. The results indicate both learned and unlearned changes in motivation for fluid following ingestion of lead via the mother's milk in infancy.read more
Citations
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Journal ArticleDOI
Behavioral effects of moderate lead exposure in children and animal models: part 1, clinical studies.
TL;DR: The effects of moderate lead exposure in children and animal models: Part 1, clinical studies and the literature review are summarized.
Journal ArticleDOI
The role of undernutrition in animal models of hyperactivity
TL;DR: It was concluded that growth retardation may partially account for behavioral effects previously attributed to the neurotoxic effects of viruses, 6-hydroxydopamine or inorganic lead.
Book ChapterDOI
Animal Models of Behavioral Effects of Early Lead Exposure
TL;DR: This paper will review the literature on animal models of the behavioral teratology of lead and only studies of laboratory animals will be included because of the greater experimental control allowable with subhuman subjects.
Journal ArticleDOI
Vulnerability to lead in protein-deprived suckling rats
TL;DR: The results imply an increased vulnerability to lead in protein-deprived rats as compared to normal rats, which was associated with higher blood lead levels than in normal rats exposed to an equivalent lead burden.
References
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Journal ArticleDOI
Specific hungers and poison avoidance as adaptive specializations of learning.
Paul Rozin,James W. Kalat +1 more
Journal ArticleDOI
Late effects of lead poisoning on mental development
TL;DR: The manifestations of acute involvement of the nervous system have been adequately described, and the gross destructive lesions in the brain consequent to acute lead encephalopathy accompanied by cerebral edema and high intracranial pressure have been recognized.
Journal ArticleDOI
Mother's milk: a determinant of the feeding preferences of weaning rat pups
Journal ArticleDOI
Hyperactivity and brain catecholamines in lead-exposed developing rats.
TL;DR: Newborn rats that suckled mothers eating a diet containing 4 percent lead carbonate display hyperactivity, aggressiveness, and excessive stereotyped behavior starting at 4 weeks of age, which suggests a relationship between central nervous system dysfunction due to lead and dopamine metabolism in brain.
Journal ArticleDOI
The exposure of children to lead.
TL;DR: Exposure to lead may be intense in children over 1 year of age living in dilapidated dwellings in which flaking leaded paint is readily accessible, and constitutes a public health problem which may be more extensive than has heretofore been thought to exist.