Open AccessJournal Article
Amphibian plasma cells.
TLDR
The cellular basis of immunoglobulin formation in cold-blooded vertebrates thus appears to be the same as that in mammals.Abstract:
Cells with the light microscopic and ultrastructural features of mamalian plasma cells were observed in lympoid tissues of long-term stimulated Bufo marinus, the marine toad. Cells with this morphology were the only cells which could be stained by the fluorescent antibody method. The cellular basis of immunoglobulin formation in cold-blooded vertebrates thus appears to be the same as that in mammals. Bufo marinus plasma cells were most abundant in the kidney lymphoid tissue, and in the margins of granulomas formed at the sites of injection of antigen in complete adjuvant.read more
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Journal Article
The immune system of cyprinid fish. Kinetics and temperature dependence of antibody-producing cells in carp (Cyprinus carpio).
TL;DR: The temperature-peak day relationship indicated that there are steps in the primary immune response of carp differing in temperature sensitivity, and the anamnestic character of the secondary response was clearly demonstrated at 24 and 20 degrees but lost at 18 degrees.
Journal Article
Cellular and humoral aspects of the primary immune response of the toad, Bufo marinus.
E Diener,J Marchalonis +1 more
TL;DR: The primary immune response of the toad to Salmonella adelaide flagella has been analysed in terms of three immunological parameters, consistent with the hypothesis that the major patterns of differentiation and proliferation of immunologically competent cells, antigen retention and immunoglobulin structure have emerged by the phylogenetic level of anuran amphibians.
Book ChapterDOI
RES Structure and Function of the Amphibia
TL;DR: In this chapter, the structure and function of the reticuloendothelial system of Aschoff is considered as well as the organs concerned with these functions in the Amphibia.
Journal ArticleDOI
Lymphopoietic Tissue and Plasma Cells in Amphibians
Ronald R. Cowden,Robert F. Dyer +1 more
TL;DR: Intracisternal accumulations of slightly electron dense material were more frequently found in Bufo marinus plasma cells than cells with undistended cisternae suggesting some specialization of these cells in cold-bloodedvertebrates.
Journal ArticleDOI
DIFFERENTIATION OF ANTIBODY-FORMING CELLS IN TOAD SPLEEN : A Study Using Density and Sedimentation Velocity Cell Separation
N. Kraft,Ken Shortman +1 more
TL;DR: An AFC differentiation sequence from a very large, light density, dividing "blast" cell to a nondividing cell with the size, density, and morphological appearance of a small lymphocyte is suggested.
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Phylogenetic studies on the immune response: I. Localization of antigens and immune response in the toad, Bufo marinus
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