Journal ArticleDOI
An adhesive factor found in strains of Escherichia coli belonging to the traditional infantile enteropathogenic serotypes
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A new adhesive factor was found to occur with greater frequency in EPEC strains and was distinct from type 1 pili and was not inhibited by the presence ofD-mannose.Abstract:
Escherichia coli strains isolated from outbreaks of diarrheal disease were tested for the presence of adhesive factors. Fifty-one of these strains belonged to traditional infantile entero-pathogenic serotypes (EPEC) and 17 belonged to other serotypes. None of these strains were enterotoxigenic and none possessed colonization factors CFA/I or CFA/II, which have been described among strains of enterotoxigenicE. coli (ETEC). EnterotoxigenicE. coli strains from patients with diarrhea and strains which were neither EPEC nor ETEC from subjects without diarrhea were also examined. By means of a tissue culture technique using HEp-2 cells, a new adhesive factor was found to occur with greater frequency in EPEC strains. The adhesive factor was found less frequently in the other groups ofE. coli studied. It was distinct from type 1 pili and was not inhibited by the presence ofD-mannose.read more
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Interaction and localization studies of enteropathogenic Escherichia coli type IV bundle-forming pilus outer membrane components.
Anu Daniel,Aparna Singh,Lynette J. Crowther,Paula J. Fernandes,Wiebke Schreiber,Michael S. Donnenberg +5 more
TL;DR: A more complete characterization of the OM subassembly was carried out using a combination of biochemical, biophysical and genetic approaches, and it was reported that targeting of BfpG to the OM was influenced by the secretin BfpB.
Journal ArticleDOI
Treatment with phenylbutyrate in a pre-clinical trial reduces diarrhea due to enteropathogenic Escherichia coli: link to cathelicidin induction
Abdullah Al-Mamun,Akhirunnessa Mily,Protim Sarker,Snigdha Tiash,Armadno Navarro,Mahmuda Akter,Kaisar A. Talukder,M. Islam,Birgitta Agerberth,Gudmundur H. Gudmundsson,Alejandro Cravioto,Rubhana Raqib +11 more
TL;DR: In conclusion, EPEC-mediated down-regulation of CAP-18 in the small intestinal epithelia was restored by phenylbutyrate treatment and was accompanied by healing of the epithelial lining, reduced shedding and virulence of EPEC and recovery from diarrhea.
Journal ArticleDOI
Catabolite repression of the adhesion of Vero cytotoxin-producing Escherichia coli of serogroups 0157 and 0111
TL;DR: The adhesion of poorly adherent strains, especially those of serogroups O111 and O157, was investigated, and it was concluded that inhibition of adhesion was due to catabolite repression.
Journal ArticleDOI
Evaluation of a multiplex PCR method to detect enteroaggregative Escherichia coli.
TL;DR: In this article, a multiplex PCR assay was designed to check aggregative adherence fimbriae (AAF/I and AAF/II), a transcriptional activator (aggR gene), the enteroaggregative heat-stable enterotoxin EAST1 (astA gene) and a cytotoxin (Pet).
References
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Manual for the identification of medical bacteria.
S. T. Cowan,K. J. Steel +1 more
TL;DR: Manual for the identification of medical bacteria as discussed by the authors, Manual for identification of Medical bacteria, مرکز فناوری اطلاعات و اشعران رسانی
Journal Article
Manual For The Identification Of Medical Bacteria
TL;DR: A manual for the identification of medical bacteria is presented for the first time in a systematic fashion.
Journal ArticleDOI
Test for Escherichia coli Enterotoxin Using Infant Mice: Application in a Study of Diarrhea in Children in Honolulu
TL;DR: Use of the infant-mouse test in a study of 37 children with diarrhea in Honolulu revealed no enterotoxin-producing coliform bacteria in the stools, in contrast to studies reported from India, where such strains were found in a large proportion of undifferentiated cases of acute diarrhea in adults.
Journal ArticleDOI
Plasmid-controlled colonization factor associated with virulence in Esherichia coli enterotoxigenic for humans.
TL;DR: It was demonstrated that E. coli H-10407, but not H10407-, possessed pilus-like surface structures which agglutinated with the specific adsorbed (anti-colonization factor) antiserum, which may play an important and possibly essential role in naturally occurring E coli enterotoxic diarrhea in man.