Journal ArticleDOI
An Efficient Solvent-Free Synthesis of Naphthopyranopyrimidines Using Heteropolyacid as an Ecofriendly Catalyst
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TLDR
In this article, an efficient, one-pot, three-component synthesis of naphthopyranopyrimidines using β-naphthol, aldehydes, and 6-amino-1,3-dimethyl uracil catalyzed by heteropolyacid has been achieved within a short period of time.Abstract:
An efficient, one-pot, three-component synthesis of naphthopyranopyrimidines using β-naphthol, aldehydes, and 6-amino-1,3-dimethyl uracil catalyzed by heteropolyacid has been achieved within a short period of time. The present methodology offers several advantages such as ecofriendly catalyst, low catalyst loading, short reaction time, simple purification procedure, and excellent yields.read more
Citations
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Synthesis of extended conjugated indolyl chalcones as potent anti-breast cancer, anti-inflammatory and antioxidant agents.
Pravin S. Bhale,Hemant V. Chavan,Sakharam B. Dongare,Sadanand N. Shringare,Yoginath B. Mule,Samadhan S. Nagane,Babasaheb P. Bandgar +6 more
TL;DR: Among the synthesized compounds, 5i and 5l were found to be active anti-inflammatory agents in addition to having noteworthy antioxidant potential and the possible use of these compounds for the design and development of novel anti-breast cancer agents is suggested.
Journal ArticleDOI
Fe3O4@MCM-48–SO3H: An efficient magnetically separable nanocatalyst for the synthesis of benzo[f]chromeno[2,3-d]pyrimidinones
TL;DR: In this article, sulfonic acid groups were grafted onto three different types of synthesized magnetic nanoparticles, namely Fe 3 O 4, Fe 3 OD 4, and Fe O 4 @MCM-48, for the synthesis of 5-aryl-1 H -benzo[ f ]chromeno[2,3 d ]pyrimidine-2,4(3 H,5 H )-dione derivatives.
Journal ArticleDOI
Synthesis of 2,4,5-triaryl and 1,2,4,5-tetraaryl imidazoles using silica chloride as an efficient and recyclable catalyst under solvent-free conditions
TL;DR: In this paper, an efficient solvent-free synthesis of various 2,4,5-triaryl imidazoles and 1,2, 4, 5-tetraaryl imidsazoles has been developed using silica chloride as a heterogeneous catalyst.
Journal ArticleDOI
Immobilization of Lewis acidic ionic liquid on perlite nanoparticle surfaces as a highly efficient solid acid catalyst for the solvent-free synthesis of xanthene derivatives
Leila Moradi,M. Mirzaei +1 more
TL;DR: In this article, perlite nanoparticles were prepared through a simple method and then modified with Lewis acidic ionic liquid (perlite NP@IL/ZrCl4) through a two step procedure.
Journal ArticleDOI
Fast and Solvent-Free Synthesis of Polyhydroquinolines Catalyzed by a Keplerate Type Giant Nanoporous Isopolyoxomolybdate as a Reusable Catalyst
TL;DR: In this article, a Keplerate type giant nanoporous isopolyoxomolybdate (Mo132) was used in the synthesis of polyhydroquinolines in high yields under solvent-free conditions at 120°C.
References
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Journal ArticleDOI
Catalysis by Heteropoly Acids and Multicomponent Polyoxometalates in Liquid-Phase Reactions
Book
Catalysis of organic reactions
TL;DR: A collection of 33 papers and posters from a conference in Boca Raton, Florida, May 1990, in which chemists from the chemical and pharmaceutical industries, and from academia, discuss their work on the use of catalysis in organic synthesis is presented in this article.
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Ueber die Synthese pyridinartiger Verbindungen aus Acetessigäther und Aldehydammoniak
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Synthesis and antitumor activity of 2,4-diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine
TL;DR: In this paper, the synthesis of 2,4-diamino-7,8-dihydro-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine (BW301U, 7) by a route that has general applicability to the preparation of many 6-(substituted benzyl) 5-methyl pyridines is described.
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Multiple Multicomponent Macrocyclizations (MiBs) : A Strategic Development Toward Macrocycle Diversity
TL;DR: Combinatorial synthetic chemistry in the macrocycle field does not yet reflect the tremendous impact of naturally occurring macrocycles in areas such as antibiotics, immunosuppressants, ion chelators, or membrane active compounds, where their success rate appears to be overproportional (in relative terms) compared to other drug types.