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Journal ArticleDOI

Antimicrobial activity studies of the binuclear metal complexes derived from tridentate Schiff base ligands

Mehmet Tümer, +3 more
- 01 Aug 1999 - 
- Vol. 24, Iss: 4, pp 414-420
TLDR
In this paper, tridentate Schiff base ligands derived from 3-hydroxysalicylaldehyde (H2L1), 4-hexylicyloxy-3-methoxy-5-aminobenzylamine (2) with a new amine N-(pyridyl)-2-hydroxy-3methoxide-5amino-4-bromosalicylamide (3-BOW) have been prepared and their metal complexes have been characterized by elemental analyses, conductivity and magnetic susceptibility measurements.
Abstract
Three novel tridentate Schiff base ligands derived from␣the 3-hydroxysalicylaldehyde (H2L1), 4-hydroxysalicylaldehyde (H2L2) and 5-bromosalicylaldehyde (H2L3) with a new amine N-(pyridyl)-2-hydroxy-3-methoxy-5-aminobenzylamine (2) have been prepared. The ligands and their metal complexes have been characterized by elemental analyses, conductivity and magnetic susceptibility measurements, i.r., electronic absorption and 1H and 13C n.m.r. spectroscopy. All complexes are binuclear and, in some, the H2O molecules are coordinated to the metal ion. Antimicrobial activities of the ligands and their complexes have been tested against to the Bacillus subtilis IMG 22 (bacteria), Micrococcus luteus LA 2971 (bacteria) Saccharamyces cerevisiae WET 136 (yeast), and Candida albicans CCM 314 (yeast). Thermal properties of all complexes have been studied by t.g. and d.t.a techniques.

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Citations
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Journal ArticleDOI

A review on versatile applications of transition metal complexes incorporating Schiff bases

TL;DR: This review compiles examples of the most promising applied Schiff bases and their complexes in different areas and explains how to understand the properties of both ligands and metal can lead to the synthesis of highly active compounds.
Journal ArticleDOI

Cd(II) and Cu(II) complexes of polydentate Schiff base ligands: synthesis, characterization, properties and biological activity

TL;DR: In this paper, the synthesis of the Schiff base ligands, 4-[(4-bromo-phenylimino)-methyl]-benzene-1,2,3-triol (A1), 4]-(3,5-di-tert-butyl-4-hydroxy-phenymalin)-methyl]benzenes- 1,2-diol (A5), and their Cd(II) and Cu(II)-metal complexes, stability constants and potentiometric studies.
Journal ArticleDOI

Metal Complexes of Quinolone Antibiotics and Their Applications: An Update

TL;DR: Interaction with metal ions has some important consequences for the solubility, pharmacokinetics and bioavailability of quinolones, and is also involved in the mechanism of action of these bactericidal agents.
Journal ArticleDOI

Synthesis, structure, antioxidation, and DNA-binding studies of a binuclear ytterbium(III) complex with bis( N -salicylidene)-3-oxapentane-1,5-diamine

TL;DR: A new complex of ytterbium(III) nitrate with bis(N-salicylidene)-3-oxapentane-1,5-diamine (H2L), with the composition Yb2(L)2(NO3)2·2H2O, was synthesized and characterized by physic-chemical and spectroscopic methods as mentioned in this paper.
Journal Article

In Vitro Antibacterial Studies of Ciprofloxacin-imines and Their Complexes with Cu(II),Ni(II),Co(II), and Zn(II)

TL;DR: It was found that metal complexes are more antibacterial as compared to uncomplexed ligands in the search of a target antibiotic instead of a broad spectrum one.
References
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Journal ArticleDOI

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Journal ArticleDOI

The infrared spectra and structure of complexes of copper(II) halides and heterocyclic bases

TL;DR: In this paper, the effect of co-ordination on the fundamental vibrations of the ligand has been considered and the order of relative basic strengths has been derived from the CuN frequencies.
Journal ArticleDOI

Cobalt(II), nickel(II), copper(II), thorium(IV) and uranium(VI) complexes of some heterocyclic Schiff bases derived from hydroxy aromatic aldehydes and 2-aminopyridine

TL;DR: In this article, it was shown that the neutral molecules and not anions of 2-aminopyridine with salicylaldehyde are coordinated to the metal ion as monodentate ligand where the nitrogen pyridine ring is the bonding site.
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