Journal ArticleDOI
Applications of crotyldiisopinocampheylboranes in synthesis: a formal total synthesis of (+)-calyculin A
Oren P. Anderson,Anthony G. M. Barrett,Jeremy J. Edmunds,Shun ichiro Hachiya,James A. Hendrix,Kiyoshi Horita,James W. Malecha,Christopher J. Parkinson,Andrew Vansickle +8 more
TLDR
The formal total synthesis of the marine metabolite (+)-calyculin A was reported in this article, which involved the use of Brown allylboration chemistry to control the relative and absolute stereochemis...Abstract:
The formal total synthesis of the marine metabolite (+)-calyculin A is reported. The key steps involve (i) the use of Brown allylboration chemistry to control the relative and absolute stereochemis...read more
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Recent advances in the total syntheses of oxazole-containing natural products
TL;DR: A review focusing on recently completed total syntheses of natural products that contain oxazole moieties as part of their structures covering literature up to December 2003 is presented in this paper.
Journal ArticleDOI
Transition Metal-Catalyzed Organometallic Reactions that Have Revolutionized Organic Synthesis
TL;DR: The Pd- or Ni-catalyzed cross-coupling reactions of organometals containing Zn, Al, Zr, and B as well as related reactions of Mg and several other metals collectively represent the most widely applied crosscoupled reactions.
Journal ArticleDOI
Polyketide stereotetrads in natural products
TL;DR: This tutorial review attempts an analysis indicating the salient features of the structural classes with examples of the synthesis of each one of them, choosing polyketides as the particular class of natural products.
Journal ArticleDOI
Apoptolidin: induction of apoptosis by a natural product.
TL;DR: The known synthetic routes to apoptolidin are described and compared and selected further natural products which regulate apoptosis are introduced briefly.
Journal ArticleDOI
Stereoselective syntheses of (+)-goniodiol, (-)-8-epigoniodiol, and (+)-9-deoxygoniopypyrone via alkoxyallylboration and ring-closing metathesis.
TL;DR: A convenient synthesis of (+)-goniodiol, (-)-8-epigoniodol, and (+)-9-deoxygoniopypyrone has been developed via asymmetric alkoxyallylboration and ring-closing metathesis pathways.
References
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Protective groups in organic synthesis
TL;DR: In this article, the most useful groups for the hydroxyl, amino, carboxyl, carbonyl, and sulfhydryl groups are discussed and the chemistry of the classes of these groups, as well as that of individual groups within the class using structures, equations and references.
Journal ArticleDOI
.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines
Journal ArticleDOI
A useful 12-I-5 triacetoxyperiodinane (the Dess-Martin periodinane) for the selective oxidation of primary or secondary alcohols and a variety of related 12-I-5 species
Daniel B. Dess,J. C. Martin +1 more