Assessment of Antimicrobial Effectiveness of Neem and Clove Extract Against Streptococcus mutans and Candida albicans: An In vitro Study.
Vaibhav Bansal,Manoj Kumar Gupta,Tapas Bhaduri,Sufiyan Shaikh,Fazlur Rahman Sayed,Vkalp Bansal,Ankita Agrawal +6 more
TLDR
The result of the study established that both plant extracts possess antimicrobial activity against common microbes present in the oral cavity.Abstract:
Background: There is increasing interest to develop antimicrobial aids from alternative sources such as medicinal plants for the treatment of infectious diseases. Neem and clove are known to have antimicrobial properties. Aim: The study aimed at detecting the antibacterial and antifungal activity of neem and clove extract against Streptococcus mutans and Candida albicans. Materials and Methods: Strains of S. mutans and C. albicans and selective media for growing micro-organisms were procured. Antimicrobial activity was assessed using two methods, by determining the minimum inhibitory concentration (MIC) using the broth dilution method and determining the zone of inhibition using well diffusion method on mitis salivarius bacitracin selective for S. mutans and Saboraud's dextrose agar plates for C. albicans. One way ANOVA with post hoc analysis was done to compare the antimicrobial activity of extracts and 0.2% chlorhexidine. Results: MIC of neem extract was found to be 4.2 mg/ml and 5.0 mg/ml against S. mutans and C. albicans, respectively. While for cloves, it was 5.5 mg/ml for both. Neem had the highest antibacterial activity with a mean zone of inhibition of 11.4 mm followed by chlorhexidine and cloves whereas antifungal activity was highest for chlorhexidine (14.4 mm) followed by neem and clove. Conclusion: The result of the study established that both plant extracts possess antimicrobial activity against common microbes present in the oral cavity.read more
Citations
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References
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Journal Article
Biological activities and medicinal properties of neem (Azadirachta indica)
TL;DR: This review gives a bird’s eye view mainly on the biological activities of some of the neem compounds isolated, pharmacological actions ofThe neem extracts, clinical studies and plausible medicinal applications of neem along with their safety evaluation.
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Compounds from Syzygium aromaticum possessing growth inhibitory activity against oral pathogens
Lining Cai,Christine D. Wu +1 more
TL;DR: A crude MeOH extract of Syzygium aromaticum (clove) exhibited preferential growth-inhibitory activity against Gram-negative anaerobic periodontal oral pathogens, including Porphyromonas gingivalis and Prevotella intermedia.
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Synergistic effect between clove oil and its major compounds and antibiotics against oral bacteria
TL;DR: The results suggest that the clove oil and eugenol could be employed as a natural antibacterial agent against cariogenic and periodontopathogenic bacteria.
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Evaluation of the antimicrobial activity of various concentrations of Tulsi (Ocimum sanctum) extract against Streptococcus mutans: an in vitro study.
TL;DR: Tulsi extract demonstrated an antimicrobial property against Streptococcus mutans and was the widest zone of inhibition observed among all the 15 different concentrations of Tulsi that were investigated.
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The antimicrobial activity of Azadirachta indica, Mimusops elengi, Tinospora cardifolia, Ocimum sanctum and 2% chlorhexidine gluconate on common endodontic pathogens: An in vitro study
TL;DR: The Methanolic extract of A.Indica, O.sanctum, M. Elengi, T.cardifolia and Chlorhexidine Gluconate has considerable antimicrobial activity against S. faecalis and S. aureus.