Association between iron status, iron deficiency anaemia, and severe early childhood caries: a case-control study.
Robert J Schroth,Jeremy A. Levi,Eleonore Kliewer,James K. Friel,Michael E. K. Moffatt,Michael E. K. Moffatt +5 more
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Children with S-ECC appear to be at significantly greater odds of having low ferritin status compared with caries-free children and also appear to have significantly lower haemoglobin levels than the carie's-free control group.Abstract:
Severe tooth decay is known to affect the health and well-being of young children. However, little is known about the influence of Severe Early Childhood Caries (S-ECC) on childhood nutritional status. The purpose of this study was to contrast ferritin and haemoglobin levels between preschoolers with S-ECC and caries-free controls. Children were recruited as part of a larger case–control study examining differences in nutritional status between those with and without S-ECC. Preschoolers with S-ECC were recruited on the day of their dental surgery, while caries-free controls were recruited from the community. Parents completed a questionnaire and the child underwent venipuncture. The study was approved by the University’s Health Research Ethics Board. Statistics included descriptive, bivariate and logistic regression analyses. A p value ≤ .05 was significant. A total of 266 children were recruited; 144 with S-ECC and 122 caries-free. The mean age was 40.8 ± 14.1 months. The mean ferritin concentration for all children was 29.6 ± 17.9 μg/L while the mean haemoglobin level was 115.1 ± 10.1 g/L. Children with S-ECC were significantly more likely to have low ferritin (p=.033) and low haemoglobin levels (p>.001). Logistic regression analyses revealed that children with S-ECC were nearly twice as likely to have low ferritin levels and were over six times more likely to have iron deficiency anaemia than caries-free controls. Children with S-ECC appear to be at significantly greater odds of having low ferritin status compared with caries-free children and also appear to have significantly lower haemoglobin levels than the caries-free control group. Children with S-ECC also appear to be at significantly greater odds for iron deficiency anaemia than cavity-free children.read more
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Topical ferumoxytol nanoparticles disrupt biofilms and prevent tooth decay in vivo via intrinsic catalytic activity.
Yuan Liu,Pratap C. Naha,Geelsu Hwang,Dongyeop Kim,Yue Huang,Aurea Simon-Soro,Hoi In Jung,Zhi Ren,Yong Li,Sarah Gubara,Faizan Alawi,Domenick T. Zero,Anderson T. Hara,David P. Cormode,Hyun Koo +14 more
TL;DR: Topical oral treatment with ferumoxytol and H2O2 suppresses the development of dental caries in vivo, preventing the onset of severe tooth decay (cavities) in a rodent model of the disease.
Journal ArticleDOI
Vitamin D status of children with severe early childhood caries: a case–control study
Robert J Schroth,Jeremy A. Levi,Elizabeth Sellers,James K. Friel,Eleonore Kliewer,Michael E. K. Moffatt,Michael E. K. Moffatt +6 more
TL;DR: Children with S-ECC appear to have relatively poor nutritional health compared to caries-free controls, and were significantly more likely to have low vitamin D, calcium, and albumin concentrations and elevated PTH levels.
Journal ArticleDOI
Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood caries
Elisha Riggs,Nicky Kilpatrick,Linda Slack-Smith,Barbara Lesley Chadwick,Jane Yelland,Murugan Satta Muthu,Judith C Gomersall +6 more
TL;DR: To assess the effects of interventions with pregnant women, new mothers or other primary caregivers of infants in the first year of life, for preventing early childhood caries, randomised controlled trials were performed in high-, middle- and low-income countries.
Journal ArticleDOI
The Burden of Early Childhood Caries in Canadian Children and Associated Risk Factors.
Andrew Pierce,Andrew Pierce,Sarbjeet Singh,Sarbjeet Singh,JuHae Lee,JuHae Lee,Cameron G. Grant,Cameron G. Grant,Vivianne Cruz de Jesus,Robert J Schroth,Robert J Schroth +10 more
TL;DR: Current literature reveals that many Canadian children are affected by ECC, and the development of ECC appears to be strongly associated with social determinants of health including low household income and the level of parental education or employment status.
Journal ArticleDOI
Factors Associated With Dental Care Utilization in Early Childhood
Denise Darmawikarta,Yang Chen,Sarah Carsley,Catherine S Birken,Patricia C. Parkin,Robert J Schroth,Jonathon L Maguire +6 more
TL;DR: Among healthy urban children seen by a primary care provider, those most susceptible to cavities were least likely to receive early dental care and underscore the importance for primary care physicians to promote dental care in early childhood.
References
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TL;DR: Comprehensive dental rehabilitation resulted in catch-up growth, such that children with a history of nursing caries no longer differed in percentile weights from comparison patients.
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