Association of Type and Duration of Diabetes With Erectile Dysfunction in a Large Cohort of Men
Constance G. Bacon,Frank B. Hu,Edward Giovannucci,Dale B. Glasser,Murray A. Mittleman,Eric B. Rimm +5 more
TLDR
For men over age 50 years, increasing duration of diabetes was positively associated with increased risk of ED relative to nondiabetic subjects, and this association persisted despite the higher prevalence of other comorbid conditions.Abstract:
OBJECTIVE —Differences in risk of erectile dysfunction (ED) by characteristics of diabetes among older men are not well understood. We examined the association of type and duration of diabetes with erectile function in men >50 years of age in a large prospective cohort study. RESEARCH DESIGN AND METHODS —Subjects included 31,027 men aged 53–90 years in the Health Professionals Follow-Up Study cohort. On a questionnaire mailed in 2000, participants rated their ability (without treatment) in the past 5 years to have and maintain an erection sufficient for intercourse. Men who reported poor or very poor function were considered to have ED. Diabetes information was ascertained via self-report and documented with supplementary medical data. RESULTS —Men with diabetes had an age-adjusted relative risk (RR) of 1.32 (95% CI 1.3–1.4) for having ED compared with men without diabetes. In multivariable regression analyses, men with type 1 and type 2 diabetes were at a significantly higher risk for ED (type 1 diabetes RR = 3.0, 95% CI 1.5–5.9; type 2 diabetes RR = 1.3, 1.1–1.5) than nondiabetic men. Men with type 2 diabetes had an increasingly greater risk of ED with increased duration since diagnosis (trend test P value 20 years previously). CONCLUSIONS —For men over age 50 years, increasing duration of diabetes was positively associated with increased risk of ED relative to nondiabetic subjects. This association persisted despite the higher prevalence of other comorbid conditions. ED prevention and diabetes management efforts are likely to go hand-in-hand.read more
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Diabetic Autonomic Neuropathy
TL;DR: There are studies in progress that suggest that autonomic nerves can be induced to regenerate, and the future for patients with diabetic autonomic neuropathy is brighter.
Journal ArticleDOI
Diabetic neuropathies: a statement by the American Diabetes Association.
Andrew J.M. Boulton,Andrew J.M. Boulton,Arthur I. Vinik,Joseph C. Arezzo,Vera Bril,Eva L. Feldman,Roy Freeman,Rayaz A. Malik,Raelene E. Maser,Jay M. Sosenko,Dan Ziegler +10 more
TL;DR: Not all patients with peripheral nerve dysfunction have a neuropathy caused by diabetes, and effective symptomatic treatments are available for the manifestations of DPN and autonomic neuropathy.
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The multinational Men's Attitudes to Life Events and Sexuality (MALES) study: I. Prevalence of erectile dysfunction and related health concerns in the general population.
TL;DR: The MALES study confirms the high prevalence rates of erectile dysfunction and its association with co-morbid medical conditions, such as diabetes and depression, reported in other large-scale, epidemiological studies.
Journal ArticleDOI
Erectile Dysfunction: AUA Guideline.
Arthur L. Burnett,Ajay Nehra,Rodney H. Breau,Daniel J. Culkin,Martha M. Faraday,Lawrence S. Hakim,Joel J. Heidelbaugh,Mohit Khera,Kevin T. McVary,Martin Miner,Christian J. Nelson,Hossein Sadeghi-Nejad,Allen D. Seftel,Alan W. Shindel +13 more
TL;DR: This document is designed to be used in conjunction with the associated treatment algorithm, and all patients should be informed of all treatment modalities that are not contraindicated, regardless of invasiveness or irreversibility, as potential first‐line treatments.
Journal ArticleDOI
Erectile Dysfunction in Diabetes Mellitus
TL;DR: A holistic approach is needed in the management of diabetic ED, which is multifactorial in aetiology and is more severe and more resistant to treatment compared with nondiabetic ED.
References
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