Journal ArticleDOI
Asymmetric synthesis mediated by chiral ligands
TLDR
Chiral chelated lithium amides were designed and synthesized in this article for enantioselective reactions such as deprotonation of prochiral cyclic ketones, kinetic resolution of racemic 2-substituted cyclohexanones, and deracemization of chiral ketones by protonation.Abstract:
Chiral chelated lithium amides were designed and synthesized. Studies have been done to explore the use of these lithium amides or their corresponding amines for enantioselective reactions such as deprotonation of prochiral cyclic ketones, kinetic resolution of racemic 2-substituted cyclohexanones by deprotonation, regioselective deprotonation of optically active 3-keto steroids, alkylation of achiral ketones, and deracemization of chiral ketones by protonation. Approaches to catalytic asymmetric deprotonation and alkylation are also attempted.read more
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TADDOLs, Their Derivatives, and TADDOL Analogues: Versatile Chiral Auxiliaries
TL;DR: TADDOLs are the most effective doping agents known for phase transformations of achiral (nematic) into chiral (cholesteric) liquid crystals and show further unusual characteristics that make them useful for applications in material science and supramolecular chemistry.
Journal ArticleDOI
Enantioselektive Synthese mit Lithium/(−)‐Spartein‐Carbanion‐Paaren
Dieter Hoppe,T. Hense +1 more
TL;DR: In this paper, der Kniff besteht in der Verwendung von Lithium-Kationen mit chiralen Liganden, sei es bei der kinetisch gesteuerten enantiotopos-differenzierenden Deprotonierung with Alkyllithiumverbindungen als Base oder bei the thermodynamisch gestuerten Gleichgewichtseinstellung in konfigurativ labilen, epimeren Ionenpaaren.
Journal ArticleDOI
Mixed AggregAte (MAA): a single concept for all dipolar organometallic aggregates. 2. Syntheses and reactivities of homo/heteroMAAs.
TL;DR: Syntheses and Reactivities of Homo/HeteroMAAs Florence Mongin* and Anne Harrison-Marchand.
Journal ArticleDOI
Mixed AggregAte (MAA): A Single Concept for All Dipolar Organometallic Aggregates. 1. Structural Data
TL;DR: Organometallic Aggregates.
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