Bioactive versatile azomethine complexes of organotin(IV) and organosilicon(IV)

TLDR: In this paper, Diorganotin(IV) and diorganosilicon (IV) derivatives of the types R 2 MCl(TSCZ), where TSCZ is the anion of a thiosemicarbazone ligand, R = Ph or Me and M = Sn or Si) have been synthesized and characterized by elemental analyses, molecular weight determinations and conductivity measurements.

Abstract: Diorganotin(IV) and diorganosilicon(IV) derivatives of the types R 2 MCl(TSCZ) and R 2 M(TSCZ) 2 (where TSCZ is the anion of a thiosemicarbazone ligand, R = Ph or Me and M = Sn or Si) have been synthesized and characterized by elemental analyses, molecular weight determinations and conductivity measurements. The mode of bonding has been established on the basis of IR and 1 H, 13 C 29 Si and 119 Sn NMR spectroscopic studies. Some of the representative complexes have also been evaluated for their antimicrobial effects on different species of pathogenic fungi and bacteria in vivo as well as in vitro. The results of these investigations are reported.