Journal ArticleDOI
Blood lipid profile and BMI-Z-score in adolescents with hyperuricemia
TLDR
The results of this study confirm higher prevalence of hyperuricemia in males when compared to females and a stronger association of HU with BMI-Z-score and lipid profile in male adolescents and multiple regression does not confirm the independent association of SUA with lipid profile.Abstract:
Numerous studies have demonstrated that elevated serum uric acid concentration (SUA) is correlated with lipid profile in hypertensive or obese patients. However, the relationship between serum uric acid levels and lipid profile in non-obese late adolescent population was not examined before. In this study we decided to assess the potential relationship between SUA and lipid profile, according to gender in adolescents with HU. The study group comprises 607 Polish adolescents (474 males, 133 females) with HU. Retrospective analysis included demographic, clinical, and laboratory data. Lipid profile was assessed including total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), total cholesterol to HDL-C ratio (TC/HDL-C). In the examined group 187/607 (31 %) of teenagers were diagnosed with metabolic syndrome (MetS). Median BMI-Z-score was 1.11 Q1–Q3: (−0.02–2.03) and both females and males in the upper tertile of SUA had statistically significant higher BMI-Z-score. The males in the upper tertile of serum uric acid levels also had higher values of TG and lower of HDL-C. In females, we have not found significant differences in lipid profile. Multiple regression analyses indicated that male gender, BMI-Z-score, and presence of hypertension correlated significantly with serum uric acid concentration. In summary, the results of our study confirm higher prevalence of hyperuricemia in males when compared to females and a stronger association of HU with BMI-Z-score and lipid profile in male adolescents. Nevertheless, multiple regression does not confirm the independent association of SUA with lipid profile.read more
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Association between dyslipidemia and serum uric acid levels in Korean adults: Korea National Health and Nutrition Examination Survey 2016-2017.
TL;DR: It is demonstrated that the dyslipidemia components of serum total cholesterol, triglycerides and LDL-C levels are positively associated with serum uric acid levels, whereas serum HDL-C Levels are inversely related.
Journal ArticleDOI
Risk factors for the development of hyperuricemia: A STROBE-compliant cross-sectional and longitudinal study.
TL;DR: This study revealed that the change of diastolic blood pressure (DBP), serum triglycerides (TG), blood urea nitrogen (BUN), creatinine, and high-density lipoprotein cholesterol (HDL-C) level were independently associated with incident hyperuricemia.
Journal ArticleDOI
Insulin resistance surrogates predict hypertension plus hyperuricemia.
Yaxin Li,Aijun You,Brian Tomlinson,Brian Tomlinson,Longfei Yue,Kanjie Zhao,Huimin Fan,Liang Zheng +7 more
TL;DR: In this article, the authors compared the association of hypertension plus hyperuricemia with four insulin resistance surrogates, including glucose and triglycerides (TyG index), TyG index with body mass index, TG/HDL-C and metabolic score for insulin resistance (METS-IR).
Journal ArticleDOI
Elevated triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio increased risk of hyperuricemia: a 4-year cohort study in China
Xinyao Liu,Wu Qiaoyu,Zhiheng Chen,Guangyu Yan,Yao Lu,Haijiang Dai,Ying Li,Pingting Yang,Hong Yuan +8 more
TL;DR: Wang et al. as discussed by the authors investigated the relationship between triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio and the risk of hyperuricemia in Chinese population.
Journal ArticleDOI
Higher triglyceride level predicts hyperuricemia: A prospective study of 6-year follow-up.
Yuan Zhang,Fengjiang Wei,Chen Chen,Chunyou Cai,Kai Zhang,Ning Sun,Jianli Tian,Wentao Shi,Miaomiao Zhang,Yong Zang,Jiani Song,Yukun He,Jiayi Feng,Qianqian Zhou,Mengyan Li,Pufei Bai,Shuzhi Feng,Weidong Li +17 more
TL;DR: In this article, the authors explored the relationship between TG levels and hyperuricemia in a dynamic cohort established in 2009 and found that higher TG levels predicted higher incidences of HUA in a dosedependent relationship.
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