Body mass index and thromboembolic stroke in nonsmoking men in older middle age. The Honolulu Heart Program.
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It is concluded that elevated body mass is associated with an increased risk of thromboembolic stroke in nonsmoking men in older middle age who are free of commonly observed conditions related to cardiovascular disease.Abstract:
While evidence suggests that obesity has an independent relation to coronary artery disease, similar findings for stroke have not been established. The purpose of this study was to examine the relation between body mass index and the risk of thromboembolic stroke independently of other risk factors.Since 1965, the Honolulu Heart Program has followed a cohort of men in a prospective study of cardiovascular disease. This article examines the relationship between the baseline measurement of body mass index and the risk of thromboembolic stroke in 1163 nonsmoking men in older middle age (55 to 68 years). Men who had an elevated risk of stroke due to hypertension, diabetes, and other risk factors were excluded from the analysis.After 22 years of follow-up, the rate of stroke increased significantly with increasing levels of body mass (P < .01). In the bottom tertile of the body mass index, the rate of thromboembolic stroke was 28.7 per 1000 (11/383). In the middle tertile, the rate was increased by 40% to 40.7...read more
Citations
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Obesity and Cardiovascular Disease: Pathophysiology, Evaluation, and Effect of Weight Loss
Paul Poirier,Thomas D. Giles,George A. Bray,Yuling Hong,Judith S. Stern,F. Xavier Pi-Sunyer,Robert H. Eckel +6 more
TL;DR: The available evidence of the impact of obesity on CVD is reviewed with emphasis on the evaluation of cardiac structure and function in obese patients and the effect of weight loss on the cardiovascular system.
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Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic Attack : A statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke : Co-sponsored by the Council on Cardiovascular Radiology and Intervention : The American Academy of Neurology affirms the value of this guideline
Ralph L. Sacco,Robert J. Adams,Greg Albers,Mark J. Alberts,Oscar R. Benavente,Karen L. Furie,Larry B. Goldstein,Philip B. Gorelick,Jonathan L. Halperin,Robert E. Harbaugh,S. Claiborne Johnston,Irene L. Katzan,Margaret Kelly-Hayes,Edgar J. Kenton,Michael P. Marks,Lee H. Schwamm,Thomas A. Tomsick +16 more
TL;DR: In this paper, the authors provide comprehensive and timely evidence-based recommendations on the prevention of ischemic stroke among survivors of stroke or transient ischemi stroke, including the control of risk factors, interventional approaches for atherosclerotic disease, antithrombotic treatments for cardioembolism, and the use of antiplatelet agents for noncardioembolic stroke.
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Guidelines for Prevention of Stroke in Patients With Ischemic Stroke or Transient Ischemic Attack
Ralph L. Sacco,Robert J. Adams,Greg Albers,Mark J. Alberts,Oscar Benavente,Karen L. Furie,Larry B. Goldstein,Philip B. Gorelick,Jonathan L. Halperin,Robert E. Harbaugh,S. Claiborne Johnston,Irene L. Katzan,Margaret Kelly-Hayes,Edgar J. Kenton,Michael P. Marks,Lee H. Schwamm,Thomas A. Tomsick +16 more
TL;DR: Evidence-based recommendations are included for the control of risk factors, interventional approaches for atherosclerotic disease, antithrombotic treatments for cardioembolism, and the use of antiplatelet agents for noncardioembolic stroke.
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JBS 2: Joint British Societies' guidelines on prevention of cardiovascular disease in clinical practice
Diabetes Uk,Heart Uk +1 more
TL;DR: The Joint British Societies’ guidelines (JBS 2) on cardiovascular disease prevention in clinical practice were developed by a Working Party with nominated representatives from six professional societies to promote a consistent multidisciplinary approach to the management of people with established atherosclerotic cardiovascular disease (CVD) and those at high risk of developing symptomatic atherosclerosis.
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A Prospective Study of Body Mass Index, Weight Change, and Risk of Stroke in Women
Kathryn M. Rexrode,Charles H. Hennekens,Walter C. Willett,Graham A. Colditz,Meir J. Stampfer,Janet W. Rich-Edwards,Frank E. Speizer,JoAnn E. Manson +7 more
TL;DR: Obesity and weight gain in women are important risk factors for ischemic and total stroke but not hemorrhagic stroke, according to prospective data from the Nurses' Health Study, which examined the associations of body mass index (BMI) and weight change with risk of stroke in women.
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