J
J. Michael Gaziano
Researcher at Brigham and Women's Hospital
Publications - 666
Citations - 59816
J. Michael Gaziano is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Risk factor & Medicine. The author has an hindex of 115, co-authored 579 publications receiving 52562 citations. Previous affiliations of J. Michael Gaziano include Veterans Health Administration & Boston University.
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Journal ArticleDOI
Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT).
Scott M. Lippman,Eric A. Klein,Eric A. Klein,Phyllis J. Goodman,M. Scott Lucia,Ian M. Thompson,Leslie G. Ford,Howard L. Parnes,Lori M. Minasian,J. Michael Gaziano,Jo Ann Hartline,J. Kellogg Parsons,James D. Bearden,E. David Crawford,Gary E. Goodman,Jaime Claudio,Eric Winquist,Elise D. Cook,Daniel D. Karp,Philip J. Walther,Michael M. Lieber,Alan R. Kristal,Amy K. Darke,Kathryn B. Arnold,Patricia A. Ganz,Regina M. Santella,Demetrius Albanes,Philip R. Taylor,Jeffrey L. Probstfield,T. J. Jagpal,John Crowley,Frank L. Meyskens,Laurence H. Baker,Charles A. Coltman +33 more
TL;DR: Selenium or vitamin E, alone or in combination at the doses and formulations used, did not prevent prostate cancer in this population of relatively healthy men.
Journal ArticleDOI
A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women
Paul M. Ridker,Nancy R. Cook,I-Min Lee,David Gordon,J. Michael Gaziano,JoAnn E. Manson,Charles H. Hennekens,Julie E. Buring +7 more
TL;DR: This large, primary-prevention trial among women showed that aspirin significantly reduced the risk of major cardiovascular events, ischemic stroke, and myocardial infarction among women 65 years of age or older.
Journal ArticleDOI
Vitamin E and the Risk of Prostate Cancer: The Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Eric A. Klein,Ian M. Thompson,Catherine M. Tangen,John Crowley,M. Scott Lucia,Phyllis J. Goodman,Lori M. Minasian,Leslie G. Ford,Howard L. Parnes,J. Michael Gaziano,Daniel D. Karp,Michael M. Lieber,Philip J. Walther,Laurence Klotz,J. Kellogg Parsons,Joseph L. Chin,Amy K. Darke,Scott M. Lippman,Gary E. Goodman,Frank L. Meyskens,Laurence H. Baker +20 more
TL;DR: Dietary supplementation with vitamin E significantly increased the risk of prostate cancer among healthy men in relatively healthy men.
Journal ArticleDOI
Vitamin E in the Primary Prevention of Cardiovascular Disease and Cancer The Women's Health Study: A Randomized Controlled Trial
I-Min Lee,Nancy R. Cook,J. Michael Gaziano,David Gordon,Paul M. Ridker,JoAnn E. Manson,Charles H. Hennekens,Julie E. Buring +7 more
TL;DR: The data from this large trial indicated that 600 IU of natural-source vitamin E taken every other day provided no overall benefit for major cardiovascular events or cancer, did not affect total mortality, and decreased cardiovascular mortality in healthy women.
Journal ArticleDOI
C-Reactive Protein, Fibrinogen, and Cardiovascular Disease Prediction
Stephen Kaptoge,Emanuele Di Angelantonio,Lisa Pennells,Angela M. Wood,Ian R. White,Pei Gao,Matthew G. Walker,Alexander M. W. Cargill Thompson,Nadeem Sarwar,Muriel J. Caslake,Adam S. Butterworth,Philippe Amouyel,Gerd Assmann,Stephan J. L. Bakker,Elizabeth L M Barr,Elizabeth Barrett-Connor,Emelia J. Benjamin,Cecilia Björkelund,Hermann Brenner,Eric J. Brunner,Robert Clarke,Jackie A. Cooper,Peter Cremer,Mary Cushman,Gilles R. Dagenais,Ralph B. D'Agostino,Rachel Dankner,George Davey-Smith,Dorly J. H. Deeg,Jacqueline M. Dekker,Gunnar Engström,Aaron R. Folsom,F. Gerry R. Fowkes,John Gallacher,J. Michael Gaziano,Simona Giampaoli,Richard F. Gillum,Albert Hofman,Barbara V. Howard,Erik Ingelsson,Hiroyasu Iso,Torben Jørgensen,Stefan Kiechl,Akihiko Kitamura,Yutaka Kiyohara,Wolfgang Koenig,Daan Kromhout,Lewis H. Kuller,Debbie A Lawlor,Tom W. Meade,Aulikki Nissinen,Børge G. Nordestgaard,Altan Onat,Demosthenes B. Panagiotakos,Bruce M. Psaty,Beatriz L. Rodriguez,Annika Rosengren,Veikko Salomaa,Jussi Kauhanen,Jukka T. Salonen,Jonathan A. Shaffer,Steven Shea,Ian Ford,Coen D.A. Stehouwer,Timo E. Strandberg,Robert W. Tipping,Alberto Tosetto,Sylvia Wassertheil-Smoller,Patrik Wennberg,Rudi G. J. Westendorp,Peter H. Whincup,Lars Wilhelmsen,Mark Woodward,Gordon D.O. Lowe,Nicholas J. Wareham,Kay-Tee Khaw,Naveed Sattar,Chris J. Packard,Vilmundur Gudnason,Paul M. Ridker,Mark B. Pepys,Simon G. Thompson,John Danesh +82 more
TL;DR: It is estimated that under current treatment guidelines, assessment of the CRP or fibrinogen level in people at intermediate risk for a cardiovascular event could help prevent one additional event over a period of 10 years for every 400 to 500 people screened.