Journal ArticleDOI
Borrowing hydrogen in the activation of alcohols
TLDR
In this paper, the metal catalyst returned the hydrogen to the transformed carbonyl compound, leading to an overall process in which alcohols can be converted into amines, compounds containing CC bonds and β-functionalised alcohols.Abstract:
Alcohols can be temporarily converted into carbonyl compounds by the metal-catalysed removal of hydrogen. The carbonyl compounds are reactive in a wider range of transformations than the precursor alcohols and can react in situ to give imines, alkenes, and α-functionalised carbonyl compounds. The metal catalyst, which had borrowed the hydrogen, then returns it to the transformed carbonyl compound, leading to an overall process in which alcohols can be converted into amines, compounds containing CC bonds and β-functionalised alcohols.read more
Citations
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N-Heterocyclic Carbenes in Late Transition Metal Catalysis
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Dehydrogenation as a substrate-activating strategy in homogeneous transition-metal catalysis.
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Applications of acceptorless dehydrogenation and related transformations in chemical synthesis.
TL;DR: Acceptorless dehydrogenation and related dehydrogenative coupling reactions have the potential for redirecting synthetic strategies to the use of sustainable resources, devoid of toxic reagents and deleterious side reactions, with no waste generation.
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Hydrogen autotransfer in the N-alkylation of amines and related compounds using alcohols and amines as electrophiles.
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Dehydrogenation and related reactions catalyzed by iridium pincer complexes
TL;DR: McDonald et al. as mentioned in this paper proposed a method to solve the problem of protein synthesis in the context of the 239th American Chemical Society (ACS) National Meeting of Organometallics 2010.
References
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Journal ArticleDOI
Asymmetric Catalysis by Architectural and Functional Molecular Engineering: Practical Chemo‐ and Stereoselective Hydrogenation of Ketones
Ryoji Noyori,Takeshi Ohkuma +1 more
TL;DR: The newly devised [RuCl(2)(phosphane)(2)(1,2-diamine)] complexes are excellent precatalysts for homogeneous hydrogenation of simple ketones which lack any functionality capable of interacting with the metal center.
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Asymmetric transfer hydrogenation: chiral ligands and applications
TL;DR: In this tutorial review the most significant advances recently achieved in the stereoselective reduction of unsaturated organic compounds catalyzed by homogeneous transition metal complexes are critically reviewed.
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Mechanistic aspects of transition metal-catalyzed hydrogen transfer reactions.
TL;DR: In this tutorial review recent mechanistic studies on transition metal-catalyzed hydrogen transfer reactions are discussed and an important question is whether the substrate coordinates to the metal (inner-sphere hydrogen transfer) or if there is a direct concerted transfer of hydrogen from the metal to substrate (outer-spheres hydrogen transfer).
Journal ArticleDOI
Asymmetric hydrogen transfer reactions promoted by homogeneous transition metal catalysts
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Facile Conversion of Alcohols into Esters and Dihydrogen Catalyzed by New Ruthenium Complexes
TL;DR: In this paper, an efficient, environmentally benign method for the preparation of esters from alcohols under mild, neutral conditions without the need for carboxylic acid derivatives and condensing agents was developed.