Journal ArticleDOI
Brain lesions manifesting as psychiatric disorders: eight cases.
Adomas Bunevicius,Vytenis Pranas Deltuva,Daiva Deltuviene,Arimantas Tamašauskas,Robertas Bunevičius +4 more
TLDR
This study presents eight cases of patients with brain lesions who, for a significant period of time, were diagnosed and treated for psychiatric disorders and show that brain tumors can be neurologically silent for a sufficient period ofTime and manifest as psychiatric disorders.Abstract:
Sometimes patients with organic brain lesions in neurologically silent brain areas might present only with psychiatric symptoms, such as depression, anxiety disorders, schizophrenia, anorexia nervosa, or cognitive dysfunction. This study presents eight cases of patients with brain lesions (four cases of meningiomas, one case of intracerebral cysts, one case of anaplastic oligodendroglioma, one case of multiform glioblastoma, and one case of occlusive hydrocephalus) who, for a significant period of time, were diagnosed and treated for psychiatric disorders (three cases of Alzheimer's disease, two cases of schizoaffective disorder, one case of schizophrenia, one case of depression, and one case of organic emotional lability disorder). When neurologic symptoms developed, they underwent neuroimaging studies and organic brain lesions were diagnosed. Further treatment required neurosurgical interventions. These cases show that brain tumors can be neurologically silent for a sufficient period of time and manifest as psychiatric disorders. Therefore, neuroimaging studies are needed when atypical changes in mental status or neurologic symptoms and signs develop.read more
Citations
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Journal ArticleDOI
Tumor infiltrating immune cells in gliomas and meningiomas
Patrícia Domingues,María González-Tablas,Álvaro Otero,Daniel Pascual,David Miranda,Laura Ruiz,Pablo Sousa,Juana Ciudad,Jesús María Gonçalves,Maria do Carmo Lopes,Alberto Orfao,María Dolores Tabernero +11 more
TL;DR: Current knowledge about tumor-infiltrating immune cells in the two most common types of CNS tumors-gliomas and meningiomas are summarized, as well as the role that such immune cells may play in the tumor microenvironment in controlling and/or promoting tumor development, growth and control.
Journal ArticleDOI
Psychiatric aspects of brain tumors: A review.
TL;DR: A comprehensive review of the literature regarding reports of brain tumors and psychiatric symptoms from 1956-2014 was conducted by as mentioned in this paper, which yielded case reports, case studies, and case series, and no double blind studies except for post-diagnosis/-surgery studies.
Journal ArticleDOI
Mood and anxiety disorders as early manifestations of medical illness: a systematic review
TL;DR: Depression was found to be the most common affective prodrome of medical disorders and was consistently reported in Cushing's syndrome, hypothyroidism, hyperparathyroidism), pancreatic and lung cancer, myocardial infarction, Wilson's disease, and AIDS.
Journal ArticleDOI
Modifications of default-mode network connectivity in patients with cerebral glioma.
TL;DR: Modifications of DMN connectivity were induced by gliomas and differed for high and low grade tumors, but not in the high-grade tumor patients.
Journal ArticleDOI
Brain tumor location and psychiatric symptoms: is there any association? A meta-analysis of published case studies
Subramoniam Madhusoodanan,Mark Opler,Despina Moise,Jessica Gordon,Deepa Danan,Abhishek Sinha,Ramesh Babu +6 more
TL;DR: Results demonstrated that there is a statistically significant association between anorexia symptoms and hypothalamic tumors, and several of the brain regions demonstrated an increased likelihood of associated symptoms when compared with other regions.
References
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Book
The Merck Manual of Diagnosis and Therapy
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Toshiaki Onitsuka,Martha E. Shenton,Dean F. Salisbury,Chandlee C. Dickey,Kiyoto Kasai,Sarah Toner,Melissa Frumin,Ron Kikinis,Ferenc A. Jolesz,Robert W. McCarley +9 more
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Kiyoto Kasai,Martha E. Shenton,Dean F. Salisbury,Yoshio Hirayasu,Toshiaki Onitsuka,Magdalena H. Spencer,Deborah A. Yurgelun-Todd,Ron Kikinis,Ferenc A. Jolesz,Robert W. McCarley +9 more
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Detection of grey matter loss in mild Alzheimer's disease with voxel based morphometry
Giovanni B. Frisoni,C. Testa,A Zorzan,Francesca Sabattoli,A. Beltramello,Hilkka Soininen,Mikko P. Laakso +6 more
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