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Journal ArticleDOI

C8-amino purine nucleosides. A well-defined steric determinant of glycosyl conformational preferences.

Frank Jordan, +1 more
- 17 Jun 1977 - 
- Vol. 476, Iss: 4, pp 265-271
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TLDR
Temperature dependent behavior of chemical shifts and the difference in chemical shifts between the C1'-H and C2'-H resonances clearly indicated whether the nucleoside exists in a syn glycosyl conformation or as a flexible syn-anti mixture (the monomethylamino and amino derivatives).
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This article is published in Biochimica et Biophysica Acta.The article was published on 1977-06-17. It has received 39 citations till now. The article focuses on the topics: Chemical shift & Conformational isomerism.

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Journal ArticleDOI

A non-empirical chromophoric interpretation of CD spectra of DNA G-quadruplex structures

TL;DR: The case of quadruplexes formed by monomeric guanosine derivatives, where there is no strand connecting the adjacent quartets and the definition parallel/antiparallel strands cannot apply, will be discussed.
Journal ArticleDOI

Recognition of Thymine Adenine Base Pairs by Guanine in a Pyrimidine Triple Helix Motif

TL;DR: A study of 20 base triplets reveals that the triple helix can be extended from homopurine to mixed sequences, and Guanine contained within a pyrimidine oligonucleotide specifically recognizes thymine.
Book ChapterDOI

Circular dichroism of quadruplex structures.

TL;DR: In this chapter the CD spectral features characteristic of different folding topologies of G4-DNA are analyzed in terms of the sequence of the syn or anti glycosidic bond angle (GBA) within a quadruplex stem.
Journal ArticleDOI

DNA base modification: ionized base pairs and mutagenesis

TL;DR: The model presented in this study should be useful as DNA-sequence analysis becomes more commonly applied to the study of mutagenesis, and as DNA structure at and surrounding ionized base pairs may be altered.
Journal ArticleDOI

Effects of an 8-bromodeoxyguanosine incorporation on the parallel quadruplex structure [d(TGGGT)]4

TL;DR: The conformational features found in the three quadruplexes might, in principle, amplify the range of applicability of synthetic oligonucleotides as aptamers or catalysts, by providing novel structural motifs with different molecular recognition capabilities from those of native DNA sequences.
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