Journal ArticleDOI
Cancer Stage‐to‐Age Relationship: Implications for Cancer Screening in the Elderly*
Frederick F. Holmes,Hearne Erwin +1 more
TLDR
The inverse relationship of age to stage in bronchial cancer suggests that screening by periodic chest roentgenograms and cytologic sputum examinations may be more appropriate for elderly than for younger populations in whom these screening methods have proved disappointing.Abstract:
In a study specifically addressing the age-stage relationship, the authors examined the distribution of 30,991 cancers by disease-stage versus patient-age at the time of diagnosis. For cancer of the bladder, breast, cervix, ovary and uterus (endometrium), a highly significant positive relationship was found between advancing stage and advancing age (P less than 0.001). For cancer of the kidney and stomach, the relationship held but was less significant (P less than 0.05). For colorectal cancer, no relationship was evident. For bronchial cancer there was a highly significant inverse relationship (P less than 0.001). After the site of origin of the cancer, the stage at the time of diagnosis was the next most important determinant for treatment and survival. These data emphasize the importance of periodic pelvic examination as a means of screening for asymptomatic cervical, ovarian, or other uterine (endometrial) cancer in elderly women. Also, the data support the importance of breast self-examination and mammography in screening for breast cancer in older women. The inverse relationship of age to stage in bronchial cancer suggests that screening by periodic chest roentgenograms and cytologic sputum examinations may be more appropriate for elderly than for younger populations in whom these screening methods have proved disappointing.read more
Citations
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Journal ArticleDOI
Patterns of care related to age of breast cancer patients
TL;DR: It is concluded that physicians may manage patients with this highly treatable disease according to chronologic age without regard for physiological condition and that this age bias may result in a less favorable prognosis than could be achieved using currently recommended therapy.
Journal ArticleDOI
Comorbidity and age as predictors of risk for early mortality of male and female colon carcinoma patients : A population-based study
Rosemary Yancik,Margaret N. Wesley,Lynn A. G. Ries,M.P.H. Richard J. Havlik M.D.,B A Sherrill Long,Brenda K. Edwards,M.P.H. Jerome W. Yates M.D. +6 more
TL;DR: P preexisting diseases in older colon carcinoma patients at diagnosis are documents and the effects of their comorbidity burden on early mortality are evaluated.
Journal ArticleDOI
Breast cancer in aging women. A population-based study of contrasts in stage, surgery, and survival.
TL;DR: Elderly women do as well as younger patients in survival time for localized and regional stages of breast cancer; for distant disease, they fare worse; results emphasize the need to focus on elderly women for screening, early detection, diagnostic evaluation, and therapy.
Journal ArticleDOI
Patient delay and stage of diagnosis among breast cancer patients in Germany – a population based study
TL;DR: It is suggested that at risk groups for delaying consultation can be identified and that a substantial proportion of late stage diagnoses of poorly differentiated breast cancer cases could be avoided if all patients with breast cancer symptoms would present to a doctor within 1 month.
Journal ArticleDOI
Determinants of late stage diagnosis of breast and cervical cancer: the impact of age, race, social class, and hospital type.
TL;DR: Logistic regression analyses demonstrated that, in New York City, older Black, lower class women in public hospitals were 3.75 and 2.54 times more likely to have late stage breast or cervical cancer, respectively, than were younger White, high social classWomen in non-public hospitals.
References
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Journal ArticleDOI
Breast self-examination practices and breast-cancer stage.
Roger S. Foster,Sandra P. Lang,Michael C. Costanza,John K. Worden,Carleton R. Haines,Jerome W. Yates +5 more
TL;DR: More frequent performance of breast self-examination was associated with more favorable clinical stage and fewer axillary-lymph-node metastases on histologic examination, and data associating more favorableclinical and pathological stages of breast cancer with more frequent breastSelf-examination need to be extended by determination of the survival rates of the various self- examination groups.
Journal ArticleDOI
Estimated Effect of Breast Self-Examination and Routine Physician Examinations on Breast-Cancer Mortality
Peter Greenwald,Philip C. Nasca,Charles E. Lawrence,John Horton,Robert P. McGarrah,Thomas Gabriele,Kathleen Carlton +6 more
TL;DR: The effects of breast self-examination and breast examination by physicians on the stage of breast cancer at diagnosis and the estimate that breast-cancer mortality might be reduced by 18.8% to 24.4% through self- examination or routine physician examination, respectively.
Journal ArticleDOI
Breast cancer in 3,558 women: age as a significant determinant in the rate of dying and causes of death.
Mueller Cb,Ames F,Anderson Gd +2 more
TL;DR: The forces of mortality created by cancer of the breast have been examined utilizing data collected during the past 19 years by the Syracuse, N. Y., Upstate Medical Center Cancer Registry on 3,558 women.
Journal ArticleDOI
Is curable lung cancer detected by semiannual screening
TL;DR: For ten years, a population of 6,136 male volunteers aged 45 years and over was screened every six months with 70-mm chest photofluorograms and with questionnaires regarding symptoms; 121 developed bronchogenic carcinoma.