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Open AccessJournal ArticleDOI

Candida-associated denture stomatitis.

TLDR
A correct oral hygiene is important for the control of the bacterial biofilm present on the denture and on the oral mucosa and it is the fundamental base for the prophylaxis and the therapy of the Candida-associated denture stomatitis.
Abstract
Candida albicans is a dimorphic yeast strongly gram positive able to live as normal commensal organism in the oral cavity of healthy people. It is the yeast more frequently isolated in the oral cavity. Under local and systemic factors related to the host conditions, it becomes virulent and responsible of oral diseases known as oral candidiasis. It has been shown that the presence of denture is a predisposing factor to the onset of pathologies related to C. albicans. Clinical studies have shown that C. albicans is not only able to adhere to the mucous surfaces, but also to stick to the acrylic resins of the dental prostheses. Both the plaque accumulated on the denture and the poor oral hygiene contribute to the virulence of Candida, offering the clinical picture of Candida-associated denture stomatitis. The therapeutic strategies currently adopted in the clinical practice to overcome these fungal infections provide for the use of topical and/or systemic antifungal and topical antiseptics and disinfectants, the irradiation with microwaves and the accurate mechanical removal of the bacterial plaque from the denture surfaces and from the underlying mucosa. A correct oral hygiene is important for the control of the bacterial biofilm present on the denture and on the oral mucosa and it is the fundamental base for the prophylaxis and the therapy of the Candidaassociated denture stomatitis.

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Polymicrobial Interactions: Impact on Pathogenesis and Human Disease

TL;DR: A review of polymicrobial biofilm-mediated infections examines the contribution of bacterial-bacterial, bacterial-fungal, and bacterial-viral interactions during human infection and potential strategies for protection against such diseases.
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Pathogenesis and treatment of oral candidosis

TL;DR: The aim of this review is to give the reader a contemporary overview of oral candidosis, the organisms involved, and the management strategies that are currently employed or could be utilised in the future.
Book ChapterDOI

The Oral Microbiota.

TL;DR: The most common strategy and the golden standard for the prevention of caries, gingivitis and periodontitis is the mechanical removal of this biofilms from teeth, restorations or dental prosthesis by regular toothbrushing.
Journal ArticleDOI

Silver colloidal nanoparticles: antifungal effect against adhered cells and biofilms of Candida albicans and Candida glabrata

TL;DR: Silver nanoparticles (SN) may have the potential to be an effective alternative to conventional antifungal agents for future therapies in Candida-associated denture stomatitis.
Journal ArticleDOI

Development and Validation of an In Vivo Candida albicans Biofilm Denture Model

TL;DR: The mucosal host response to the denture biofilm and found the mucosal histopathology to be consistent with that of acute human denture stomatitis, demonstrating fungal invasion and neutrophil infiltration.
References
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Journal ArticleDOI

An epidemiologic study of yeasts in elderly denture wearers.

TL;DR: The study has revealed that candida infection and poor denture cleanliness are very common in elderly denture wearers.
Journal ArticleDOI

Candida-associated denture stomatitis. Aetiology and management: a review. Part 2. Oral diseases caused by Candida species.

TL;DR: Current studies indicate that denture stomatitis lesions are associated with the detection of candida species while other factors such as denture hygiene, trauma, systemic diseases and deficiencies of the immune system may be involved.
Journal ArticleDOI

Candida-associated denture stomatitis. Aetiology and management: a review. Part 1. Factors influencing distribution of Candida species in the oral cavity.

TL;DR: There is clear evidence that C. albicans adheres to oral surfaces including acrylic dentures and mucosa, with the mechanisms of attachment under the control of hydrophobic and electrostatic forces and adhesion to mucosa dependent on a number of complex ligand-recognition systems.
Journal Article

Candida albicans, Staphylococcus aureus and Streptococcus mutans colonization in patients wearing dental prosthesis

TL;DR: This illness-bearing condition is more frequent in patients with denture stomatitis, even though dental prosthesis colonization is lower than in the oral mucous, and its relationship with other potential clinical co-factors is investigated.
Journal ArticleDOI

Candida-associated denture stomatitis. Aetiology and management: a review. Part 3. Treatment of oral candidosis

TL;DR: Treatment of oral candidosis with topical antifungal agents such as nystatin and amphotericin B is effective initially but medication can produce side effects in some patients and when therapy is stopped the condition can recur.
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