Journal ArticleDOI
Catalytic Asymmetric Allenylation: Regulation of the Equilibrium between Propargyl- and Allenylstannanes during the Catalytic Process.
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TLDR
Achiral substrates 1 and 2 can be regioselectively converted into chiral allenyl alcohols 3 through the title reaction with the synergetic reagent iPrSBEt2 and a chiral TiIV catalyst.Abstract:
Achiral substrates 1 and 2 can be regioselectively converted into chiral allenyl alcohols 3 through the title reaction [Eq. (1)] with the synergetic reagent iPrSBEt2 and a chiral TiIV catalyst. The dramatic regioselectivity originates from the regulation of the equilibrium between propargyl- and allenylstannanes during the catalytic process.read more
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Journal ArticleDOI
Catalytic Enantioselective Addition of Allylic Organometallic Reagents to Aldehydes and Ketones
Scott E. Denmark,Jiping Fu +1 more
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Polysaccharide-based chiral stationary phases for high-performance liquid chromatographic enantioseparation.
TL;DR: A review of polysaccharide-based chiral stationary phases (CSPs) for the direct separation of enantiomers in high-performance liquid chromatography (HPLC) is presented in this article.
Journal ArticleDOI
How easy are the syntheses of allenes
Shichao Yu,Shengming Ma +1 more
TL;DR: Allenes have proven themselves to be valuable building blocks toward complex molecular targets, revealing novel applications in natural product synthesis, pharmaceutical chemistry and materials science, and some of the recent important developments on the synthesis of allenes are highlighted.
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