Journal ArticleDOI
Catheter mapping of spontaneous and induced atrial fibrillation in man.
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TLDR
It is concluded that regional catheter mapping of AF is feasible and safe in man and organized electrical activity is frequently observed at AF onset in patients with heart disease.Abstract:
The clinical electrophysiologic study of atrial fibrillation [AF] has recently progressed from static characterization of the substrate to the dynamic investigation of both induced and spontaneous AF in man. Prior studies have demonstrated inhomogeneity and greater dispersion of atrial refractoriness in patients with AF, but recently atrial electrical remodeling with consequent abbreviation of atrial refractory periods has also been reported. Yet further experimental observations have suggested the existence of additional arrhythmogenic mechanisms for certain AF subsets. These include studies that have demonstrated a stable atrial “flutter” circuit in one atrium with fibrillatory conduction or a “focal” atrial tachyarrhythmia arising commonly in the left atrium.read more
Citations
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Journal ArticleDOI
International consensus on nomenclature and classification of atrial fibrillation; a collaborative project of the Working Group on Arrhythmias and the Working Group on Cardiac Pacing of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology.
Samuel Levy,Alan John Camm,Sanjeev Saksena,Etienne Aliot,G. Breithardt,Harry J.G.M. Crijns,W. Davies,N. Kay,Eric N. Prystowsky,Richard Sutton,Albert L. Waldo,D. G. Wyse +11 more
TL;DR: This document reports the conclusions reached by this Study Group during a meeting held on June, 13, 2000, and completed by the members soon thereafter, in an attempt to achieve a consensus on the terminology and classification of AF.
Journal ArticleDOI
Therapeutic implications of atrial fibrillation mechanisms: can mechanistic insights be used to improve AF management?
TL;DR: What is known about the mechanistic substrates that lead to atrial fibrillation are reviewed and the potential therapeutic consequences are discussed.
Journal ArticleDOI
International consensus on nomenclature and classification of atrial fibrillation: A collaborative project of the Working Group on Arrhythmias and the Working Group of Cardiac Pacing of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology.
Samuel Lévy,A. John Camm,Sanjeev Saksena,Etienne Aliot,Günter Breithardt,Harry J.G.M. Crijns,D. Wyn Davies,G. Neal Kay,Eric N. Prystowsky,Richard Sutton,Albert L. Waldo,D. George Wyse +11 more
TL;DR: This document reports the conclusions reached by this Study Group during a meeting held on June, 13, 2000, and completed by the members soon thereafter, in an attempt to achieve a consensus on the terminology and classification of AF.
Journal ArticleDOI
Atrial fibrillation recurrence after internal cardioversion: prognostic importance of electrophysiological parameters
TL;DR: Patients with failed external cardioversion or long lasting AF may benefit from internal atrial cardioversion and antiarrhythmic treatment to keep SR at long term; electrophysiological study may identify patients at the highest risk of arrhythmia recurrence.
Journal ArticleDOI
Cardiac cellular heterogeneity and remodelling
TL;DR: In normal heart, the time-to-peak of contraction decreases from endocardium to epicardium which, in the presence of a corresponding delay in transmural activation timing, supports synchronised peak force development of the tissue as a whole.
References
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Journal ArticleDOI
Atrial Fibrillation Begets Atrial Fibrillation A Study in Awake Chronically Instrumented Goats
TL;DR: Artificial maintenance of AF leads to a marked shortening of AERP, a reversion of its physiological rate adaptation, and an increase in rate, inducibility and stability of AF.
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A computer model of atrial fibrillation.
TL;DR: The model exhibited self-sustained turbulent activity having many similarities to atrial fibrillation, and suggests the formulation of a “fibrillation” number, similar in concept to the Reynolds number related to turbulence in fluid flow.
Journal ArticleDOI
A Focal Source of Atrial Fibrillation Treated by Discrete Radiofrequency Ablation
Pierre Jaïs,Michel Haïssaguerre,D. C. Shah,Salah Chouairi,L Gencel,Mélèze Hocini,Jacques Clementy +6 more
TL;DR: In some patients, the surface ECG pattern of atrial fibrillation is due to a focal rapidly firing source of activity that can be eliminated by discrete radiofrequency energy applications.
Journal ArticleDOI
High-density mapping of electrically induced atrial fibrillation in humans.
Karen T. S. Konings,Charles J. H. J. Kirchhof,Joep R. L. M. Smeets,Hein J.J. Wellens,Olaf C. Penn,Maurits A. Allessie +5 more
TL;DR: In this article, the authors reconstruct and classify the patterns of human right atrial (RA) activation during electrically induced atrial fibrillation (AF) in humans, based on multiple reentering wavelets.
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