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Open AccessJournal ArticleDOI

Cerebral near-infrared spectroscopy monitoring and neurologic outcomes in adult cardiac surgery patients: a systematic review.

TLDR
Reductions in rScO2 during cardiac surgery may identify cardiopulmonary bypass cannula malposition, particularly during aortic surgery, and data are insufficient to conclude that interventions to improve r ScO2 desaturation prevent stroke or POCD.
Abstract
Background Near-infrared spectroscopy is used during cardiac surgery to monitor the adequacy of cerebral perfusion. In this systematic review, we evaluated available data for adult patients to determine (1) whether decrements in cerebral oximetry during cardiac surgery are associated with stroke, postoperative cognitive dysfunction (POCD), or delirium and (2) whether interventions aimed at correcting cerebral oximetry decrements improve neurologic outcomes.

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Journal ArticleDOI

NIRS in clinical neurology - a 'promising' tool?

Hellmuth Obrig
- 15 Jan 2014 - 
TL;DR: Near-infrared spectroscopy has become a relevant research tool in neuroscience and the potential to exploit the established position of NIRS as a functional imaging tool with regard to clinical questions such as preoperative functional assessment and neurorehabilitation is discussed.
Journal ArticleDOI

Postoperative Cognitive Dysfunction: Minding the Gaps in our Knowledge of A Common Postoperative Complication in the Elderly

TL;DR: In this article, the literature on POCD and POCI is reviewed, current research challenges in this area are discussed, and present research challenges are discussed.
Journal ArticleDOI

Duration and magnitude of blood pressure below cerebral autoregulation threshold during cardiopulmonary bypass is associated with major morbidity and operative mortality.

TL;DR: Blood pressure management during cardiopulmonary bypass using physiologic endpoints such as cerebral autoregulation monitoring might provide a method of optimizing organ perfusion and improving patient outcomes from cardiac surgery.
Journal ArticleDOI

Perioperative organ injury.

TL;DR: The authors are of the opinion that research to provide mechanistic insight into acute organ injury and identification of novel therapeutic approaches for the prevention or treatment of perioperative organ injury represent the most important opportunity to improve outcomes of anesthesia and surgery.
References
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Journal ArticleDOI

Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters

TL;DR: Observations by infrared transillumination in the exposed heart and in the brain in cephalo without surgical intervention show that oxygen sufficiency for cytochrome a,a3, function, changes in tissue blood volume, and the average hemoglobin-oxyhemoglobin equilibrium can be recorded effectively and in continuous fashion for research and clinical purposes.
Journal ArticleDOI

Limits of the 'Mini-Mental State' as a screening test for dementia and delirium among hospital patients

TL;DR: The MMSE's value as a screen instrument for dementia and delirium when later, more intensive diagnostic enquiry is possible is confirmed; earlier suggestions that the MMSE alone cannot yield a diagnosis for these conditions are reinforced.
Journal ArticleDOI

Monitoring brain oxygen saturation during coronary bypass surgery: a randomized, prospective study.

TL;DR: Monitoring cerebral rSO2 in coronary artery bypass patients avoids profound cerebral desaturation and is associated with significantly fewer incidences of major organ dysfunction.
Journal ArticleDOI

Near-infrared spectroscopy as an index of brain and tissue oxygenation

TL;DR: A review of the mode of operation, current limitations and confounders, clinical applications, and potential future uses of such NIRS-based cerebral oximetry devices can be found in this article.
Journal ArticleDOI

Cerebral Oxygen Desaturation Predicts Cognitive Decline and Longer Hospital Stay After Cardiac Surgery

TL;DR: Intraoperative cerebral oxygen desaturation is significantly associated with an increased risk of cognitive decline and prolonged hospital stay after CABG.
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