Chromosome studies in 12 solid tumours from children.
TLDR
All photographs courtesy of AFP, AP, EPA, Getty Images and Reuters.Abstract:
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Citations
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Chromosomal aberrations in human neuroblastomas.
TL;DR: A 1 p‐ deletion was the most consistent abnormality found in the six human neuroblastomas examined in this study, and it is attempted to correlate this finding with Knudson's hypothesis on the origin of childhood cancer.
Journal ArticleDOI
Structural chromosomal abnormalities in human medulloblastoma
TL;DR: The findings suggest that the primary karyotypic deviations of human medulloblastomas are gains of whole chromosomes, which are then either deleted or involved in unbalanced translocations, resulting in partial trisomies.
Journal ArticleDOI
Medulloblastoma: tumor biological and clinical perspectives.
TL;DR: Recent studies have greatly enhanced understanding of the biology, phenotype, genotype, and therapy of medulloblastoma and further efforts to integrate laboratory and clinical studies of this tumor may allow design of novel therapeutic approaches resulting in enhanced disease-free survival.
Journal ArticleDOI
Cytogenetic studies of human brain tumors and their clinical significance. 1. Medulloblastoma.
TL;DR: In this article, four medulloblastomas were studied cytogenetically with clinical follow-up of the patients and three of these lesions were diploid and the patients manifested no recurrence at 40, 37 and 36 months respectively.
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Chromosomes and causation of human cancer and leukemia. VIII. DMS chromosomes in a neuroblastoma
TL;DR: The authors favor the concept that the DMS may represent chromomeres which have been set free, with the exact agent causing this being unknown.
References
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Journal ArticleDOI
The pathology of the tumours of children.
TL;DR: This book should be used as a supplement to the wellknown 'Pathology of Tumours' and 'Borderland', and the volume's chief value is in the extensive list of references to articles on tumours that it contains with Willis's usual cryptic comments.