Journal ArticleDOI
Chronic work stress and exhaustion is associated with higher allostastic load in female school teachers.
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Investigating the relationship between work-related chronic stress as well as exhaustion and a cumulative measure of physiological wear-and-tear called allostatic load found it to be a possible biological pathway for how chronic work stress and exhaustion lead to health impairments in the long run.Abstract:
Epidemiological studies have shown that chronic work stress or unfavourable psychosocial work conditions are prospectively associated with different adverse health outcomes. The aim of the present cross-sectional study was to investigate the relationship between work-related chronic stress as well as exhaustion and a cumulative measure of physiological wear-and-tear called allostastic load (AL). AL could be a possible biological pathway for how chronic work stress and exhaustion lead to health impairments in the long run. As the teaching profession has been proposed to be a potentially high stressful occupation, chronic work stress (effort-reward-imbalance) and exhaustion were assessed in 104 female school teachers. AL was first analyzed according to McEwen's classical model comprised of ten parameters including cortisol, epinephrine and norepinephrine, dehydroepiandrosterone-sulphate (DHEA-S), waist/hip-ratio (WHR), glycosylated haemoglobin (HbA1c), high-density lipoprotein (HDL), total cholesterol/HDL-ratio, and systolic and diastolic blood pressure. Additionally it was extended to include tumor-necrosis-factor-alpha (TNF-alpha), C-reactive protein (CRP), fibrinogen, D-dimer, percent-body-fat, triglycerides, and glucose levels. A substantial proportion of our sample was highly exhausted whereas relatively few teachers showed high effort-reward-imbalance. AL scores were significantly higher in women high on effort-reward-imbalance or suffering from exhaustion. Although all teachers had been in a good health status, chronic work stress as well as exhaustion appears to be associated with changes in a multi-system summary indicator of physiological risk.read more
Citations
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Journal ArticleDOI
Allostatic load biomarkers of chronic stress and impact on health and cognition.
TL;DR: This article reviews theoretical and empirical work using the allostatic load model vis-à-vis the effects of chronic stress on physical and mental health and proposes policies for promoting successful aging.
Journal ArticleDOI
Work Stress and Employee Health A Multidisciplinary Review
TL;DR: In this article, the Allostatic Load model is used as an organizing framework for reviewing the vast literature that has considered health outcomes that are associated with exposure to psychosocial stressors at work.
Journal ArticleDOI
When Not Enough Is Too Much: The Role of Insufficient Glucocorticoid Signaling in the Pathophysiology of Stress-Related Disorders
TL;DR: Neuroendocrine data provide evidence of insufficient glucocorticoid signaling in stress-related neuropsychiatric disorders, including posttraumatic stress disorder and major depression, which are associated with immune system activation/inflammation, high SNS tone, and CRH hypersecretion.
Journal ArticleDOI
A Systematic Review of Allostatic Load, Health, and Health Disparities
TL;DR: This systematic review examines the empirical literature that quantifies the allostasis and allostatic load construct and evaluates the social, environmental, and genetic antecedents of AL as well as its predictive utility for a variety of health outcomes.
Journal ArticleDOI
Allostatic Load and Its Impact on Health: A Systematic Review
TL;DR: It is indicated that allostatic load and overload are associated with poorer health outcomes and an integrated approach that includes both biological markers and clinimetric criteria is recommended.
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