Journal ArticleDOI
Clinical Imaging with Transmissive Ultrasonic Computerized Tomography
TLDR
Transmission ultrasound computer-assisted tomography has been developed for detection and diagnosis of cancer in the breast and estimates of sensitivity and specificity are approaching those of X-ray mammography techniques.Abstract:
Transmission ultrasound computer-assisted tomography has been developed for detection and diagnosis of cancer in the breast. Pulses of ultrasound (8 MHz ±3 MHz) are transmitted through the breast in a coronal plane from a plurality of directions. The received signal is processed for arrival time and for changes in amplitude. The measured values for arrival time and attenuation are used in a convolution-back projection reconstruction algorithm to obtain estimates of the two-dimensional distribution of acoustic speed and attenuation within the scanned planes of the breast. Over 1000 images in breasts of approximately 150 patients have been scanned of whom 30 had biopsy proven cancer. Some common characteristics of the reconstructed images which are associated with cancer are 1) increased speed relative to the embedding tissue associated with 2) decreased attenuation in central region of the lesion usually with 3) a ring of higher attenuation at the border of the lesion. Current estimates of sensitivity and specificity of this system for cancer are approaching those of X-ray mammography techniques.read more
Citations
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Journal ArticleDOI
A Filtered Backpropagation Algorithm for Diffraction Tomography
TL;DR: The reconstruction algorithm is derived for parallel beam transmission computed tomography through two-dimensional structures in which diffraction of the insonifying beam must be taken into account and is applicable to diffraction tomography within either the first Born or Rytov approximations.
Journal ArticleDOI
Empirical relationships between acoustic parameters in human soft tissues
TL;DR: In this article, a highly significant empirical linear relationship is found between sound speed and density for a wide range of soft tissues, including adipose, parenchymal, muscular, and connective tissues as well as body fluids.
Journal ArticleDOI
In vivo breast sound-speed imaging with ultrasound tomography
TL;DR: Results suggest that, clinically, sound-speed tomograms can be used to assess breast density, as well as detect and help differentiate breast lesions, and may also be a useful tool to monitor the clinical response of breast cancer patients to neo-adjuvant chemotherapy.
Journal ArticleDOI
3D ultrasonic image feature localization based on magnetic scanhead tracking: in vitro calibration and validation
Paul R. Detmer,Gerard Bashein,Timothy Hodges,Kirk W. Beach,Eric P. Filer,David H. Burns,D.Eugene Strandness +6 more
TL;DR: The lower limits of variability to be expected from this 3D ultrasound imaging system when locating fiducial anatomical landmarks for repeated examinations of the same region of the body, and when making numerical 3D reconstructions from multiple planar images are established.
Journal ArticleDOI
Frequency dependence of ultrasound attenuation and backscatter in breast tissue
F.T. D'Astous,F.S. Foster +1 more
TL;DR: Attenuation and backscatter of ultrasound in human breast tissues were measured over the frequency range relevant to breast imaging and showed that the attenuation coefficient of homogeneous regions of infiltrating duct carcinoma was higher than that of fat but somewhat less than thatof fibrous and parenchymal tissues.
References
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Journal ArticleDOI
Three-dimensional Reconstruction from Radiographs and Electron Micrographs: Application of Convolutions instead of Fourier Transforms
TL;DR: Tests of the convolution method with computer-simulated shadowgraphs show that it is also more accurate than the Fourier transform method, and has good potentialities for application in electron microscopy and x-radiography.
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An Atlas of Subgross Pathology of the Human Breast With Special Reference to Possible Precancerous Lesions
TL;DR: One hundred ninety-six whole human breasts were examined by a sub-gross sampling technique with histologic confirmation as mentioned in this paper, which permitted the enumeration and identification of essentially all the focal dysplastic, metaplastic and neoplastic lesions.
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TL;DR: A classification of risk for developing breast cancer has been devised based solely on the appearance of the breast parenchyma by mammography by reviewing the mammograms of all women over the age of 30 who had been examined at Hutzel Hospital, Detroit.
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Principles of computer assisted tomography (CAT) in radiographic and radioisotopic imaging.
Rodney A. Brooks,G Di Chiro +1 more
TL;DR: In this paper, the limitations of present techniques, and new developments and trends are outlined, compared with conventional focal plane tomography, and methods of reconstruction-back projection, iterative reconstruction and analytic reconstruction are described.
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Reconstructive tomography and applications to ultrasonics
TL;DR: Several methods of ultrasonic tomography are discussed in this article, including methods based on geometric optics and a Doppler-oriented approach, and a major portion of the paper is concerned with introducing ways to take into account diffraction effects.