Journal ArticleDOI
Comparison of scanning electron microscopy, dynamic light scattering and analytical ultracentrifugation for the sizing of poly(butyl cyanoacrylate) nanoparticles.
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TLDR
The size distribution determined by ANUC using sedimentation velocity analysis was somewhat more complex, the size of the most abundant particles being around 184 nm, and the advantages and disadvantages of the three sizing techniques are discussed.About:
This article is published in European Journal of Pharmaceutics and Biopharmaceutics.The article was published on 2004-03-01. It has received 353 citations till now. The article focuses on the topics: Dynamic light scattering & Particle size.read more
Citations
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Journal ArticleDOI
Silver as Antibacterial Agent: Ion, Nanoparticle, and Metal
TL;DR: It can be concluded that the therapeutic window for silver is narrower than often assumed, however, the risks for humans and the environment are probably limited.
Journal ArticleDOI
Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates
TL;DR: NTA is a powerful characterization technique that complements DLS and is particularly valuable for analyzing polydisperse nanosized particles and protein aggregates.
Journal ArticleDOI
Nanoparticles for drug delivery: the need for precision in reporting particle size parameters.
TL;DR: The present review highlights the difficulties in validating the data from biodistribution studies without accurate particle size determination.
Journal ArticleDOI
Detection and characterization of engineered nanoparticles in food and the environment
TL;DR: An overview of the characteristics of nanoparticles that could affect their behaviour and toxicity, as well as techniques available for their determination are provided, which could be optimized to provide the necessary information.
Journal ArticleDOI
Research strategies for safety evaluation of nanomaterials. Part VI. Characterization of nanoscale particles for toxicological evaluation.
Kevin W. Powers,Scott C. Brown,Vijay B. Krishna,Scott Wasdo,Brij M. Moudgil,Stephen M. Roberts +5 more
TL;DR: Recommendations regarding how best to approach nanomaterial characterization include using proper sampling and measurement techniques, forming multidisciplinary teams, and making measurements as close to the biological action point as possible.
References
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Book
Dynamic Light Scattering: With Applications to Chemistry, Biology, and Physics
Bruce J. Berne,R. Pecora +1 more
TL;DR: In this paper, a comprehensive introduction to principles underlying laser light scattering focuses on time dependence of fluctuations in fluid systems and provides an introduction to theory of time correlation functions, with chapters on projection operator techniques in statistical mechanics.
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Nanoparticulate systems for brain delivery of drugs.
TL;DR: Intravenously injected doxorubicin-loaded polysorbate 80-coated nanoparticles were able to lead to a 40% cure in rats with intracranially transplanted glioblastomas 101/8, and may be especially helpful for the treatment of the disseminated and very aggressive brain tumors.
Journal ArticleDOI
Modern analytical ultracentrifugation in protein science: A tutorial review
TL;DR: Sedimentation equilibrium of proteins, including membrane proteins and glycoproteins, is the method of choice for molar mass determinations and the study of self‐association and heterogeneous interactions, such as protein–protein, protein–nucleic acid, and protein–small molecule binding.
Journal ArticleDOI
Size-distribution analysis of proteins by analytical ultracentrifugation: strategies and application to model systems.
TL;DR: It is shown that the least-squares approach ls-g*(s) can be extrapolated to infinite time by considering area divisions analogous to boundary divisions in the van Holde-Weischet method, thus allowing the transformation of interference optical data into an integral sedimentation coefficient distribution G(s).
Related Papers (5)
Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates
Dynamic Light Scattering: With Applications to Chemistry, Biology, and Physics
Bruce J. Berne,R. Pecora +1 more