Journal ArticleDOI
Concept cells: the building blocks of declarative memory functions
TLDR
It is argued that the sparse, explicit and abstract representation of these neurons is crucial for memory functions, such as the creation of associations and the transition between related concepts that leads to episodic memories and the flow of consciousness.Abstract:
Intracranial recordings in subjects suffering from intractable epilepsy — made during their evaluation for an eventual surgical removal of the epileptic focus — have allowed the extraordinary opportunity to study the firing of multiple single neurons in awake and behaving human subjects. These studies have shown that neurons in the human medial temporal lobe respond in a remarkably selective and abstract manner to particular persons or objects, such as Jennifer Aniston, Luke Skywalker or the Tower of Pisa. These neurons have been named 'Jennifer Aniston neurons' or, more recently, 'concept cells'. I argue that the sparse, explicit and abstract representation of these neurons is crucial for memory functions, such as the creation of associations and the transition between related concepts that leads to episodic memories and the flow of consciousness.read more
Citations
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Journal ArticleDOI
Episodic Memory and Beyond: The Hippocampus and Neocortex in Transformation
TL;DR: Using the component process model as a framework, and focusing on the hippocampus, its subfields, and specialization along its longitudinal axis, along with its interaction with other brain regions, this work considers these new developments and their implications for the organization of episodic memory and its contribution to functions in other domains.
Journal ArticleDOI
Human-level performance in first-person multiplayer games with population-based deep reinforcement learning.
Max Jaderberg,Wojciech Marian Czarnecki,Iain Dunning,Luke Marris,Guy Lever,Antonio García Castañeda,Charles Beattie,Neil C. Rabinowitz,Ari S. Morcos,Avraham Ruderman,Nicolas Sonnerat,Tim Green,Louise Deason,Joel Z. Leibo,David Silver,Demis Hassabis,Koray Kavukcuoglu,Thore Graepel +17 more
TL;DR: In this article, the authors demonstrate that an agent can achieve human-level performance in a popular 3D multiplayer first-person video game, Quake III Arena Capture the Flag, using only pixels and game points as input.
Journal ArticleDOI
Past, present and future of spike sorting techniques
TL;DR: This work reviews the basic concepts of spike sorting, including the requirements for different applications, together with the problems faced by presently available algorithms, and proposes a roadmap stressing the crucial points to be addressed to support the neuroscientific research of the near future.
Journal ArticleDOI
Are the Neural Correlates of Consciousness in the Front or in the Back of the Cerebral Cortex? Clinical and Neuroimaging Evidence.
Mélanie Boly,Marcello Massimini,Naotsugu Tsuchiya,Bradley R. Postle,Christof Koch,Giulio Tononi +5 more
TL;DR: This Perspective will critically review the clinical and neuroimaging evidence for the involvement of the front versus the back of the cortex in specifying conscious contents and discuss promising research avenues.
Journal ArticleDOI
Human-level performance in 3D multiplayer games with population-based reinforcement learning
Max Jaderberg,Wojciech Marian Czarnecki,Iain Dunning,Luke Marris,Guy Lever,Antonio García Castañeda,Charles Beattie,Neil C. Rabinowitz,Ari S. Morcos,Avraham Ruderman,Nicolas Sonnerat,Tim Green,Louise Deason,Joel Z. Leibo,David Silver,Demis Hassabis,Koray Kavukcuoglu,Thore Graepel +17 more
TL;DR: In this article, the authors used a two-tier optimization process in which a population of independent RL agents are trained concurrently from thousands of parallel matches on randomly generated environments, each agent learns its own internal reward signal and rich representation of the world.
References
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Journal ArticleDOI
Receptive fields, binocular interaction and functional architecture in the cat's visual cortex
David H. Hubel,Torsten N. Wiesel +1 more
TL;DR: This method is used to examine receptive fields of a more complex type and to make additional observations on binocular interaction and this approach is necessary in order to understand the behaviour of individual cells, but it fails to deal with the problem of the relationship of one cell to its neighbours.
Journal ArticleDOI
Loss of recent memory after bilateral hippocampal lesions.
TL;DR: The results of these studies point to the importance of the hippocampal complex for normal memory function in patients who had undergone similar, but less radical, bilateral medial temporallobe resections, and as a warning to others of the risk to memory involved in bilateral surgical lesions of the hippocampusal region.
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Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path.
Timothy V. P. Bliss,T. Lømo +1 more
TL;DR: The after‐effects of repetitive stimulation of the perforant path fibres to the dentate area of the hippocampal formation have been examined with extracellular micro‐electrodes in rabbits anaesthetized with urethane.
Journal ArticleDOI
Receptive fields and functional architecture of monkey striate cortex
David H. Hubel,Torsten N. Wiesel +1 more
TL;DR: The striate cortex was studied in lightly anaesthetized macaque and spider monkeys by recording extracellularly from single units and stimulating the retinas with spots or patterns of light, with response properties very similar to those previously described in the cat.