Journal ArticleDOI
Control of cerebral circulation in the neonate and infant.
TLDR
A review of age-related differences in critical values of arterial oxygen tension, arterial carbon dioxide tension, systemic arterial pressure and cerebral perfusion pressure confirms that it is necessary to establish critical values in neonates and infants for each of these variables, as well as for any possible sympathetic nervous system influences on cerebral blood flow.Abstract:
Although much information is known about the factors controlling cerebral blood flow in the adult, there are significant physiological differences between the neonate, infant, and the adult. Therefore, it is not possible directly to transfer information concerning control of cerebral blood flow in the adult to the pediatric age population. A review of age-related differences in critical values of arterial oxygen tension (PaO2), arterial carbon dioxide tension (PaCO2), systemic arterial pressure and cerebral perfusion pressure (CCP) confirms that it is necessary to establish critical values in neonates and infants for each of these variables, as well as for any possible sympathetic nervous system influences on cerebral blood flow.read more
Citations
More filters
Book
Critical Care Nursing of Infants and Children
TL;DR: The author examines the impact of the Critical Care Experience on the Family, legal Implications of Pediatric Nursing Practice, and Practice Guidelines for Pediatric Critical Care on the Practice Environment.
Journal ArticleDOI
Cerebral perfusion pressure in central nervous system infections of infancy and childhood
Kalman J. Goitein,Israel Tamir +1 more
TL;DR: Monitoring of mean arterial blood pressure and intracranial pressure in children with severe central nervous system infections will enable rapid diagnosis and initiation of treatment when cerebral perfusion pressure is reduced to critical levels, and might improve the prognosis.
Journal ArticleDOI
Impact of anesthetic agents on cerebrovascular physiology in children.
TL;DR: The understanding of the effects of anesthetic agents on the physiology of cerebral vasculature in the pediatric population has significantly increased in the past decade allowing a more rationale decision making in anesthesia management.
Journal ArticleDOI
Cerebral Perfusion Pressure and Auditory Brain-Stem Responses in Childhood CNS Diseases
TL;DR: Intracranial hypertension, complicating CNS diseases of childhood, reduces effective cerebral perfusion pressure (CPP) with resultant cerebral ischemia and the auditory brain-stem evoked response (ABR) is an important diagnostic tool that enables evaluation of brain- stem function and prognostication during the acute stage of the illness.
Journal ArticleDOI
Exogenous Norepinephrine Constricts Cerebral Arterioles via α2-Adrenoceptors in Newborn Pigs:
TL;DR: It is concluded that pial arterioles are responsive to both α1- and α2-adrenoceptor agonists, that intravenous administration of prazosin and yohimbine results in these drugs crossing the blood–brain barrier and inhibiting constrictor effects of agonists.