Correction: Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1
Shiwen Wang,Bowen Jiang,Tengfei Zhang,Lixia Liu,Yi Wang,Yi-Ping Wang,Xiufei Chen,Huaipeng Lin,L Zhou,Yukun Xia,Leilei Chen,Chen Yang,Yue Xiong,Dan Ye,Kun-Liang Guan +14 more
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TLDR
This research presents a novel probabilistic approach to estimating the response of the immune system to laser-spot assisted, 3D image recognition.Abstract:
Fig 2B contains an extra lane in the right end of the top row. The authors have provided a corrected version here.
Fig 2
KAT9 acetylates PGK1 and inhibits PGK1 activity.read more
Citations
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Extracellular ATP promotes breast cancer invasion and epithelial‐mesenchymal transition via hypoxia‐inducible factor 2α signaling
Hui Yang,Yue-Hang Geng,Peng Wang,Yan-Ting Zhou,Han Yang,Yan-Fei Huo,Hongquan Zhang,Yan Li,Hui-ying He,Xin-Xia Tian,Weigang Fang +10 more
TL;DR: It is suggested that extracellular ATP could promote breast carcinoma invasion and EMT via HIF‐2α signaling, which may be a potential target for future anti–metastasis therapy.
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Suppression of fat deposition in broiler chickens by (-)-hydroxycitric acid supplementation: A proteomics perspective.
TL;DR: The data indicated that (-)-HCA inhibited fatty acid synthesis by reducing the acetyl-CoA supply, via promotion of the tricarboxylic acid cycle (upregulation of PDHA1, PDHB, ACO2, and DLST expression) and inhibition of ME1 expression, and promoted fatty acid beta-oxidation by upregulating ECHS1 expression.
Journal ArticleDOI
Global Profiling of 2-hydroxyisobutyrylome in Common Wheat.
TL;DR: In this article, the authors reported that Khib is an evolutionarily-conserved post-translational modification (PTM) in wheat and its donators, and showed that there are 3348 Khib lysine modification sites from 1074 proteins in common wheat (Triticum aestivum L.) using affinity purification and mass spectroscopy of 2-hydroxyisobutyrylome.
Journal ArticleDOI
Global Profiling of 2-hydroxyisobutyrylome in Common Wheat
TL;DR: In this article , a total of 3348 Khib sites on 1074 proteins are identified in common wheat (Triticum aestivum L.) by using affinity purification and mass spectroscopy of 2-hydroxyisobutyrylome.
Journal ArticleDOI
ELP3 Acetyltransferase is phosphorylated and regulated by the oncogenic anaplastic lymphoma kinase (ALK)
TL;DR: This study reveals a novel regulatory mechanism for ELP3, provides an example that acetyltransferase itself can be regulated by posttranslational modification, and suggests a potential target for ALK -positive cancer therapies.
References
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Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1.
Shiwen Wang,Bowen Jiang,Tengfei Zhang,Lixia Liu,Yi Wang,Yi-Ping Wang,Xiufei Chen,Huaipeng Lin,L Zhou,Yukun Xia,Leilei Chen,Chen Yang,Yue Xiong,Dan Ye,Kun-Liang Guan +14 more
TL;DR: This study uncovers a previously unknown mechanism for the insulin and mTOR pathway in regulation of glycolytic ATP production and cellular redox potential via HDAC3-mediated PGK1 deacetylation.