Journal ArticleDOI
Corticosterone- or metapyrone-induced alterations in adrenal function and expression of the arginine vasotocin receptor VT2 in the pituitary gland of domestic fowl, Gallus gallus.
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TLDR
Findings confirm a role for AVT, mediated by the VT2 receptor, in regulating ACTH secretion during stress and suggest that corticotroph VT2 receptors levels may be dynamically regulated depending on the HPA axis activity.About:
This article is published in General and Comparative Endocrinology.The article was published on 2009-04-01. It has received 5 citations till now. The article focuses on the topics: Arginine vasopressin receptor 1B & Corticosterone.read more
Citations
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Journal ArticleDOI
A possible mechanism contributing to the synergistic action of vasotocin (VT) and corticotropin-releasing hormone (CRH) receptors on corticosterone release in birds.
TL;DR: Heterodimerization data indicate that TM-IV of the VT2R may provide an important interface for effective receptor dimerization, suggesting that direct molecular interaction betweenVT2R and CRH-R1 receptors plays a role in mediating an enhanced interaction between these two receptors.
Book ChapterDOI
Chapter 23 – Pituitary Gland
TL;DR: The functioning of the avian pituitary is comprehensively reviewed encompassing the structure and functions of the pituitaries and neuroendocrine hypothalamus, and the chemistry, expression, physiology, receptors, and control of each of the hormones are covered.
Book ChapterDOI
Chapter 26 – Adrenals
TL;DR: The avian adrenal gland plays a central role in homeostasis and is composed of chromaffin and cortical tissues that are variably intermingled, and the primary role of its secretory products is to regulate energy flow and partitioning as discussed by the authors.
Book ChapterDOI
Pituitary gland
TL;DR: The structure of avian pituitary hormones is established, e.g. α-subunit of the glycoproteins consists of 96 amino acid residues across multiple avian species as discussed by the authors .
References
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Journal ArticleDOI
Corticosteroid inhibition of ACTH secretion.
TL;DR: There is some evidence that suggests that whereas comparator elements are not reset during stress, a comparator element is reset during the course of the circadian rhythm so that different basal levels of steroid are achieved.
Journal ArticleDOI
Vasopressinergic Control of Pituitary Adrenocorticotropin Secretion Comes of Age
TL;DR: By citing examples from physiological studies on the regulation of ACTH secretion, it is shown how the multicomponent hypothalamic regulatory system operates, emphasizing the considerable signal integrating role of the adenohypophysial corticotrope cell.
Journal ArticleDOI
Regulation of pituitary ACTH secretion during chronic stress.
TL;DR: Although the exact interaction between regulatory factors and the molecular mechanisms controlling the sensitivity of the corticotroph during adaptation to chronic stress remain to be determined, it is clear that regulation of the proportional secretion of CRH and VP in the PVN, modulation of pituitary VP receptors, and the sensitivity to feedback inhibition play a critical role.
Journal ArticleDOI
Hormonal regulation of peptide receptors and target cell responses
TL;DR: Receptor number is determined by hormone-induced changes in membrane conformation, irreversible ligand binding, and processing of ligand–receptor complexes during hormone action.
Journal ArticleDOI
Corticotropin releasing factor receptors and their ligand family.
Marilyn H. Perrin,Wylie Vale +1 more
TL;DR: In this article, two CRF receptors, encoded by distinct genes, CRF-R1 and CRFR2, and that can exist in two alternatively spliced forms, have been cloned.