Decreased Beta-adrenoreceptor responsiveness as related to age, blood pressure, and plasma catecholamines in patients with essential hypertension.
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An increase in the patients' blood pressure and age is associated with a progressive reduction in /3-adrenoreceptor sensitivity and/or reactivity, which may result in unopposed a- adreooreceptor-mediated vasoconstriction and thereby contribute to the development of hypertension.Citations
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ACCF/AHA Expert Consensus Document ACCF/AHA 2011 Expert Consensus Document on Hypertension in the Elderly A Report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents
Wilbert S. Aronow,Jerome L. Fleg,Carl J. Pepine,Nancy T. Artinian,George Bakris,Alan S. Brown,Keith C. Ferdinand,Mary Ann Forciea,William H. Frishman,Cheryl Jaigobin,John B. Kostis,Giuseppi Mancia,Suzanne Oparil,Eduardo Ortiz,Efrain Reisin,Michael W. Rich,Douglas D. Schocken,Michael A. Weber,Deborah J. Wesley,Robert A. Harrington,Eric R. Bates,Deepak L. Bhatt,Charles R. Bridges,Mark J. Eisenberg,Victor A. Ferrari,John D. Fisher,Timothy J. Gardner,Federico Gentile,Michael F. Gilson,Mark A. Hlatky,Alice K. Jacobs,Sanjay Kaul,David J. Moliterno,Debabrata Mukherjee,Robert Rosenson,James H. Stein,Howard H. Weitz +36 more
TL;DR: The reader should view the expert consensus document as the best attempt of the ACCF and document cosponsors to inform and guide clinical practice in areas where rigorous evidence may not yet be available or evidence to date is not widely applied to clinical practice.
Journal Article
Adrenergic and Muscarinic Receptors in the Human Heart
TL;DR: Cardiac function is controlled by the autonomic nervous system (i.e., the sympathetic and the parasympathetic nervous systems), which act via adrenoceptors and muscarinic acetylcholine receptors, respectively.
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Exercise cardiac output is maintained with advancing age in healthy human subjects: cardiac dilatation and increased stroke volume compensate for a diminished heart rate.
Richard J. Rodeheffer,Gary Gerstenblith,Lewis C. Becker,Jerome L. Fleg,Myron L. Weisfeldt,Edward G. Lakatta +5 more
TL;DR: Although aging does not limit cardiac output per se in healthy community-dwelling subjects, the hemodynamic profile accompanying exercise is altered by age and can be explained by an age-related diminution in the cardiovascular response to beta-adrenergic stimulation.
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Plasma catecholamines and essential hypertension. An analytical review.
TL;DR: The preponderance of literature on the subject supports the hypothesis that increased plasma catecholamine concentrations occur in some patients with essential hypertension, and is consistent with a pathophysiologic role for increased sympathetic neural activity in this subgroup of hypertensive patients.
Journal ArticleDOI
ACCF/AHA 2011 expert consensus document on hypertension in the elderly: A report of the american college of cardiology foundation task force on clinical expert consensus documents
Wilbert S. Aronow,Jerome J Fleg,Carl J. Pepine,Nancy T. Artinian,George L. Bakris,Alan S. Brown,Keith C. Ferdinand,Mary Ann Forciea,William H. Frishman,Cheryl Jaigobin,John B Kostis,Giuseppi Mancia,Suzanne Oparil,Eduardo Ortiz,Efrain Reisin,Michael W. Rich,Douglas D. Schocken,Michael Weber,Deborah J. Wesley +18 more
TL;DR: The ACCF/AHA Expert Consensus Document as discussed by the authors was developed as an expert consensus document by the American College of Cardiology Foundation (ACCF) and the American Heart Association (AHA), in collaboration with the American Academy of Neurology (AAN), AAN, the American Physicians Association (ACP), American Geriatrics Society (AGS), the American Society of Hypertension (ASH), the ASCN), ASCN, ASCP, American Society for Preventive Cardiology (ASPC), the Association of Black Cardiologists (ABC), and the European
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Multivariate statistical methods
TL;DR: In this article, a text designed to make multivariate techniques available to behavioural, social, biological and medical students is presented, which includes an approach to multivariate inference based on the union-intersection and generalized likelihood ratio principles.
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Textbook of Work Physiology
Per-Olof Åstrand,Kåre Rodahl +1 more
TL;DR: Find loads of the textbook of work physiology book catalogues in this site as the choice of you visiting this page.
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Simultaneous radioenzymatic determination of plasma and tissue adrenaline, noradrenaline and dopamine within the femtomole range.
Mosé Da Prada,Gerhard Zürcher +1 more
TL;DR: A radiometric-enzymatic assay for measuring simultaneously femtomole quantities of adrenaline, noradrenaline and dopamine has been developed and promises to be a valid alternative to the gas chromatography-mass spectrometry technique.