Journal ArticleDOI
Disseminated intravascular coagulation in pregnancy: insights in pathophysiology, diagnosis and management
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TLDR
In recent years, novel diagnostic scores and treatment modalities along with bedside point-of-care tests were developed and may assist the clinician in the diagnosis and management of DIC.About:
This article is published in American Journal of Obstetrics and Gynecology.The article was published on 2015-10-01. It has received 95 citations till now. The article focuses on the topics: Placental abruption & Acute fatty liver of pregnancy.read more
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Advance in the Management of Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation
TL;DR: The ISTH DIC Scientific Standardization Committee has proposed a new category termed “sepsis-induced coagulopathy (SIC)” to facilitate earlier diagnosis of DIC and potentially more rapid interventions in these critically ill patients.
Journal ArticleDOI
New developments in nucleoside analogues biosynthesis: A review
María J. Lapponi,María J. Lapponi,Cintia W. Rivero,Cintia W. Rivero,María A. Zinni,Claudia N. Britos,Jorge A. Trelles,Jorge A. Trelles +7 more
TL;DR: A brief outline of emerging methodologies for the biosynthesis of NAs commonly used in cancer therapies and as antivirals from microbial or enzymatic sources are given, and their potential applications in the biotechnology industry are given.
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Idiopathic Fatty Liver of Pregnancy: Findings in Ten Cases
TL;DR: Ten cases of fatty liver of pregnancy reported from a large metropolitan medical center for the period 1972 to 1982 yielded new data concerning presenting signs and symptoms, laboratory features including serial clotting screens documenting disseminated intravascular coagulation (DIC), obstetric and perinatal information as well as maternal follow-up.
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Disseminated intravascular coagulation in pregnancy – Clinical phenotypes and diagnostic scores
TL;DR: The current review will present the underlying mechanisms, diagnostic scores and, in brief, a therapeutic approach for DIC in pregnancy.
References
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Journal ArticleDOI
Disseminated Intravascular Coagulation
Marcel Levi,Ten Cate H +1 more
TL;DR: Bleeding may be the presenting symptom in a patient with disseminated intravascular coagulation, a factor that can complicate decisions about treatment, and the use and subsequent depletion of platelets and coagulating proteins resulting from the ongoing coagulations may induce severe bleeding.
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Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation.
TL;DR: In this paper, the authors presented a study on the effects of haematology drugs on the development of heart disease in patients with hemophilia and showed that they are useful in the treatment of heart failure.
Journal Article
Towards Definition, Clinical and Laboratory Criteria, and a Scoring System for Disseminated Intravascular Coagulation* On behalf of the Scientific Subcommittee on Disseminated Intravascular Coagulation (DIC) of the ISTH
TL;DR: This poster presents a poster presented at the European Hemophilia and Vascular Biology Conference in Brussels, Belgium, which aims to present a probabilistic picture of the immune system’s response to blood clotting disorders.
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Guidelines for the diagnosis and management of disseminated intravascular coagulation
TL;DR: Transfusion of platelets or plasma (components) in patients with DIC should not primarily be based on laboratory results and should in general be reserved for patients who present with bleeding, but should be considered in those with active bleeding and in those requiring an invasive procedure.
Journal Article
Disseminated intravascular coagulation
Toshiaki Iba,Akio Kidokoro +1 more
TL;DR: Heparin, low molecular weight heparin, danaparoid, protease inhibitors for coagulation factors and antithrombin III are the choices for DIC, but since the selection of the drugs is different depending on the basal disease, it is important to understand the pathophysiology of the individual situation.