Journal ArticleDOI
Early intervention, untreated psychosis and the course of early schizophrenia
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TLDR
In this article, a study with young people with recent onset schizophrenia has shown that an intensive intervention programme had a beneficial effect on the occurrence of psychotic relapse and the course of psychotic syndromes.Abstract:
BACKGROUND: Studies have proved that early intervention can delay psychotic relapses, and prevent psychosocial deterioration in people with schizophrenia and related disorders. METHOD: Our study with young people with recent onset schizophrenia has shown that an intensive intervention programme had a beneficial effect on the occurrence of psychotic relapse and the course of psychotic syndromes. This effect lasted until the end of the 15-month intervention. No significant effect of the two different intervention conditions became apparent. RESULTS: The results of a follow-up study showed that this beneficial effect did not last. Fifteen per cent of the people had a psychotic relapse during the intervention, whereas 64% relapsed during follow-up. CONCLUSIONS: These results show that referral to other mental health agencies after intervention is not sufficient and that more support is required to continue disease management, medication compliance and stress managementread more
Citations
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Journal ArticleDOI
Relationship Between Duration of Untreated Psychosis and Outcome in First-Episode Schizophrenia: A Critical Review and Meta-Analysis
TL;DR: Shorter duration of untreated psychosis was associated with greater response to antipsychotic treatment, as measured by severity of global psychopathology, positive symptoms, negative symptoms, and functional outcomes.
Journal ArticleDOI
Duration of untreated psychosis: a critical examination of the concept and its importance.
Ross M.G. Norman,Ashok Malla +1 more
TL;DR: Evidence thus far suggests that DUP may be related to ease of reducing psychotic symptoms once treatment begins for first episode patients, but there is no evidence of a relationship to likelihood of relapse.
Journal ArticleDOI
Early Intervention for Psychosis
Max Marshall,John Rathbone +1 more
TL;DR: Early detection and phase-specific treatment may both be offered as supplements to standard care or may be provided through a specialized early intervention team.
Journal ArticleDOI
Reducing the duration of untreated first-episode psychosis: effects on clinical presentation.
Ingrid Melle,Tor K. Larsen,Ulrik Haahr,Svein Friis,Jan Olav Johannessen,Stein Opjordsmoen,Erik Simonsen,Bjørn Rishovd Rund,Per Vaglum,Thomas H. McGlashan +9 more
TL;DR: It is possible to reduce the DUP for first-episode patients in a defined health care area through the introduction of an early detection (ED) program, compared with parallel health care areas without an ED program (No-ED).
Journal ArticleDOI
Five-year experience of first-episode nonaffective psychosis in open-dialogue approach: Treatment principles, follow-up outcomes, and two case studies
TL;DR: The Open Dialogue (OD) family and network approach aims at treating psychotic patients in their homes as discussed by the authors, which involves the patient's social network and starts within 24 hours after contact.
References
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Journal ArticleDOI
The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
Journal ArticleDOI
Social consequences of psychiatric disorders, I: Educational attainment.
TL;DR: The results presented here show that truncated educational attainment is one of them, and debate concerning whether society can afford universal insurance coverage for the treatment of mental disorders needs to take these consequences into consideration.
Journal ArticleDOI
EPPIC: An Evolving System of Early Detection and Optimal Management
TL;DR: A framework for preventive intervention in early psychosis is outlined, based on more than a decade of experience initially gained within a first-generation model, a comprehensive "real-world" model of care targeting the multiple clinical foci underpinning the preventive task.
Journal ArticleDOI
Neuroleptics and the Natural Course of Schizophrenia
TL;DR: A reanalysis of the data indicates that early intervention with neuroleptics in first-break schizophrenic patients increases the likelihood of an improved long-term course and there is evidence that stable schizophrenia patients whose neuroleptic treatment is discontinued and have relapses may have a difficult time returning to their previous level of function.
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Duration of untreated psychosis: a critical examination of the concept and its importance.
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