Journal ArticleDOI
Echocardiographic Assessment of Left Ventricular Structure and Diastolic Filling in Elderly Subjects with Borderline Isolated Systolic Hypertension (the Framingham Heart Study)
Alex Sagie,Emelia J. Benjamin,Maurizio Galderisi,Martin G. Larson,Jane C. Evans,Deborah L. Fuller,Birgitta T. Lehman,Daniel Levy +7 more
TLDR
Borderline systolic hypertension was the most frequent form of untreated hypertension in this elderly group and the sum of LV wall thicknesses was significantly higher in borderline hypertensive subjects than in normotensive ones.Abstract:
Abnormalities in left ventricular (LV) structure and function have been shown in patients with diastolic hypertension and recently in subjects with isolated systolic hypertension. The purpose of this study was to determine whether abnormalities of cardiac structure or function are present in elderly subjects with borderline isolated systolic hypertension (defined as systolic blood pressure [BP] between 140 and 159 mm Hg, and diastolic BPread more
Citations
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Journal ArticleDOI
Cardiovascular morbidity in long-term survivors of metastatic testicular cancer.
MT Meinardi,Jourik A. Gietema,Wta van der Graaf,D. J. Van Veldhuisen,MA Runne,Wj Sluiter,Ege de Vries,Pbh Willemse,Nh Mulder,M.P. van den Berg,Dt Sleijfer,H. Schraffordt Koops +11 more
TL;DR: In long-term survivors of metastatic testicular cancer, a significantly increased risk for occurrence of cardiac events accompanied by a persisting unfavorable cardiovascular risk profile is observed.
Journal ArticleDOI
The Role of Hypertension in the Pathogenesis of Heart Failure: A Clinical Mechanistic Overview
TL;DR: The observed structural and functional changes associated with hypertension evolve over decades and are preventable with effective antihypertensive treatment and emphasize the importance of early diagnosis and effective treatment of hypertension to prevent cardiac complications.
Journal ArticleDOI
Mechanisms of Exercise Intolerance Insights From Tissue Doppler Imaging
TL;DR: E/Ea continued to be strongly associated with exercise capacity in all age groups and in those with preserved or reduced systolic function, suggesting that elevated LV filling pressures rather than slow relaxation per se reduce exercise capacity.
Journal ArticleDOI
Left Ventricular Hypertrophy: Major Risk Factor in Patients with Hypertension: Update and Practical Clinical Applications
TL;DR: With the regression of left ventricular hypertrophy, diastolic function and coronary flow reserve usually improve, and cardiovascular risk decreases, and the likelihood of sudden death in patients with hypertension decreases.
Journal ArticleDOI
Left ventricular diastolic filling in the elderly: the cardiovascular health study.
Julius M. Gardin,Alice M. Arnold,Diane E. Bild,Vivienne E. Smith,Joao A.C. Lima,H. S. Klopfenstein,Dalane W. Kitzman +6 more
TL;DR: Findings are consistent with previous reports that hypertensive subjects exhibit an abnormal relaxation pattern, whereas patients with CHF develop a pattern suggestive of an increased early diastolic left atrial-LV pressure gradient.
References
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Book
Applied Regression Analysis and Other Multivariable Methods
TL;DR: In this article, the authors compare two straight line regression models and conclude that the Straight Line Regression Equation does not measure the strength of the Straight-line Relationship, but instead is a measure of the relationship between two straight lines.
Journal ArticleDOI
Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements.
TL;DR: The survey shows significant interobserver and interlaboratory variation in measurement when examining the same echoes and indicates a need for ongoing education, quality control and standardization of measurement criteria.
Journal ArticleDOI
Echocardiographic assessment of left ventricular hypertrophy: Comparison to necropsy findings
Richard B. Devereux,Richard B. Devereux,Daniel R. Alonso,Daniel R. Alonso,Elizabeth M. Lutas,Elizabeth M. Lutas,Geoffrey J. Gottlieb,Geoffrey J. Gottlieb,E Campo,E Campo,Irene Sachs,Irene Sachs,Nathaniel Reichek,Nathaniel Reichek +13 more
TL;DR: To determine the accuracy of echocardiographic left ventricular (LV) dimension and mass measurements for detection and quantification of LV hypertrophy, results of blindly read antemortem e chocardiograms were compared with LV mass measurements made at necropsy in 55 patients.
Journal ArticleDOI
Prognostic Implications of Echocardiographically Determined Left Ventricular Mass in the Framingham Heart Study
TL;DR: The estimation of left ventricular mass by echocardiography offers prognostic information beyond that provided by the evaluation of traditional cardiovascular risk factors, and it is concluded that an increase in left Ventricular mass predicts a higher incidence of clinical events, including death, attributable to cardiovascular disease.
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Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method.
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