Journal ArticleDOI
Effect of aldosterone on electrical resistance of toad bladder.
MM Civan,RE Hoffman +1 more
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This article is published in American Journal of Physiology.The article was published on 1971-02-01. It has received 59 citations till now. The article focuses on the topics: Aldosterone & Toad.read more
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Journal ArticleDOI
Subcellular mechanisms in the action of adrenal steroids.
TL;DR: Understanding of receptor mechanisms, albeit incomplete, provides an explanation of steroid specificity and overlapping physiologic effects and enables us to design new and more potent steroid antagonists and to rationalize resistance or sensitivity of tumor cells to specific steroids.
Journal ArticleDOI
Na+ transport by rabbit urinary bladder, a tight epithelium
Simon A. Lewis,Jared M. Diamond +1 more
TL;DR: The physiological significance of Na+ absorption against steep gradients in rabbit bladder may be to maintain kidney-generated ion gradients during bladder storage of urine, especially when the animal is Na+-depleted.
Journal ArticleDOI
Modulation of cell membrane area in renal collecting tubules by corticosteroid hormones
TL;DR: It is demonstrated that significant changes in membrane area can occur in differentiated epithelia and suggest that this may be an important mechanism for modulating epithelial transport capacity.
Journal ArticleDOI
Aldosterone control of the density of sodium channels in the toad urinary bladder
Lawrence G. Palmer,Lawrence G. Palmer,Jack H. Y. Li,Jack H. Y. Li,Bernd Lindemann,Bernd Lindemann,Isidore S. Edelman,Isidore S. Edelman +7 more
TL;DR: It is proposed that, following aldosterone-induced protein synthesis, there is a reversible metabolically-dependent recruitment of preexisting Na channels from a reservoir of electrically undetectable channels.
Journal ArticleDOI
Localization of Na+-pump sites in frog skin.
TL;DR: The results support a model which depicts all the living cell layers functioning as a syncytium with regard to the active transepithelial transport of Na+.
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Active transport of sodium as the source of electric current in the short-circuited isolated frog skin.
Hans H. Ussing,K. Zerahn +1 more