Effect of pregnancy in patients with lupus nephropathy.
John P. Hayslett,Robert I. Lynn +1 more
TLDR
The present study was undertaken to characterize the clinical course of SLE in patients with lupus nephropathy during pregnancy and postpartum, and it seems likely that any bias in selection of these cases would favor those with greater severity.About:
This article is published in Kidney International.The article was published on 1980-08-01 and is currently open access. It has received 166 citations till now. The article focuses on the topics: Systemic lupus erythematosus & Nephropathy.read more
Citations
More filters
Journal Article
Sex hormones, immune responses, and autoimmune diseases. Mechanisms of sex hormone action
TL;DR: The possibility of using sex hormone modulation of immune responses for the treatment of autoimmune disorders is a promising area for future investigation.
Book
Systemic Lupus Erythematosus
TL;DR: A review of major advances in clinical issues related to systemic lupus erythematosus (SLE) published between 1995 and 2000 can be found in this paper, where the authors discuss the role of cyclophosphamide, methotrexate, antimalarials, and hormonal treatment in the management of SLE.
Journal ArticleDOI
The impact of increased lupus activity on obstetric outcomes.
TL;DR: High-activity lupus during pregnancy leads to increased premature birth and a decrease in live births, with almost one-quarter of these pregnancies resulting in fetal loss.
Journal ArticleDOI
Clinical predictors of fetal and maternal outcome in systemic lupus erythematosus: a prospective study of 103 pregnancies
J. Cortés‐Hernández,Josep Ordi-Ros,F. Paredes,M. Casellas,F. Castillo,Miquel Vilardell-Tarrés +5 more
TL;DR: Antiphospholipid antibodies, C3 hypocomplementaemia and hypertension during pregnancy were significantly associated with fetal loss, prematurity and intrauterine growth restriction.
Journal ArticleDOI
Influence of oral contraceptive therapy on the activity of systemic lupus erythematosus
Paul Jungers,Maxime Dougados,Clara Pélissier,Fréd́rique Kuttenn,Françlois Tron,Philippe Lesavre,Jean-Françlois Bach +6 more
TL;DR: Oral contraceptive therapy that used estrogens, even at low doses, often induced exacerbation of systemic lupus erythematosus activity, and pure progestogens, which were effective and devoid of such unfavorable effects, may be preferred in these patients.
References
More filters
Journal ArticleDOI
The natural history of systemic lupus erythematosus by prospective analysis.
Journal ArticleDOI
Renal involvement in systemic lupud erythematosus (SLE): a study of 56 patients emphasizing histologic classification.
Journal ArticleDOI
Systemic Lupus Erythematosus and Pregnancy
TL;DR: An understanding of the interrelations of pregnancy and systemic lupus erythematosus is of considerable clinical importance, particularly since the disease occurs most frequently in women during the reproductive age.
Journal ArticleDOI
Systemic Lupus Erythematosus in Pregnancy
Leon G. Fine,Eugene V. Barnett,Gabriel M. Danovitch,Allen R. Nissenson,Matthew E. Conolly,Stephen M. Lieb,Cynthia T. Barrett +6 more
TL;DR: The pharmacologic management of systemic lupus erythematosus does not require any important modifications in pregnant patients, however, an increase in the dosage of glucocorticoids may reduce postpartum exacerbations.