Journal ArticleDOI
Effect of Withania somnifera on Lysosomal Acid Hydrolases in Adjuvant‐induced Arthritis in Rats
TLDR
Results indicate that Withania somnifera has promising anti-arthritic activity as a result of its stabilizing action on lysosomal enzyme activity.Abstract:
The effect of Withania somnifera Linn. Dunal (Solanaceae) on adjuvant arthritic rats was studied and compared with that of indomethacin.
These results indicate that Withania somnifera has promising anti-arthritic activity as a result of its stabilizing action on lysosomal enzyme activity.
The anti-inflammatory activity of Withania somnifera was assessed by measuring paw swelling and lysosomal enzyme activity in control and experimental rats. Increased paw diameter and lysosomal enzyme activity in the arthritic animals were significantly suppressed to near normal levels in rats treated with 1000 mg kg−1Withania somnifera root powder and 3 mg kg−1 indomethacin.read more
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Journal ArticleDOI
Immunomodulatory role of Withania somnifera root powder on experimental induced inflammation: An in vivo and in vitro study.
TL;DR: The aqueous suspension of Withania somnifera root powder showed potent inhibitory activity towards the complement system, mitogen induced lymphocyte proliferation and delayed-type hypersensitivity reaction, thus it could be a candidate for developing as an immunosuppressive drug for the inflammatory diseases.
Journal ArticleDOI
Suppressive effect of Withania somnifera root powder on experimental gouty arthritis: An in vivo and in vitro study
TL;DR: Evidence is provided for the suppressive effect of W. somnifera root powder by retarding amplification and propagation of the inflammatory response without causing any gastric damage.
Journal ArticleDOI
Antiinflammatory effect of the Indian Ayurvedic herbal formulation Triphala on adjuvant-induced arthritis in mice.
TL;DR: The results obtained clearly indicate the fact that the Indian Ayurvedic herbal formulation Triphala has promising antiinflammatory activity.
Journal ArticleDOI
Protective effect of Withania somnifera root powder in relation to lipid peroxidation, antioxidant status, glycoproteins and bone collagen on adjuvant-induced arthritis in rats.
M. Rasool,P. Varalakshmi +1 more
TL;DR: The results of this study clearly indicate that W. somnifera root powder is capable of rectifying the above biochemical changes in adjuvant arthritis.
Journal ArticleDOI
Evaluation of anti-inflammatory effect of Withania somnifera root on collagen-induced arthritis in rats
Apurva Gupta,Surendra Singh +1 more
TL;DR: Administration of W. somnifera root powder to the arthritic rats significantly decreased the severity of arthritis by effectively suppressing the symptoms of arthritis and improving the functional recovery of motor activity and radiological score.
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Immunomodulatory role of Withania somnifera root powder on experimental induced inflammation: An in vivo and in vitro study.
Protective effect of Withania somnifera root powder in relation to lipid peroxidation, antioxidant status, glycoproteins and bone collagen on adjuvant-induced arthritis in rats.
M. Rasool,P. Varalakshmi +1 more