Journal ArticleDOI
Effects of a pulling force on the shape of a bound vesicle
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TLDR
A theoretical model is developed to describe the vertical pulling of vesicles adhered in a contact potential that contains regions with either a unique bound shape or an additional meta-stable shape that unbind discontinuously upon pulling.Abstract:
We develop a theoretical model to describe the vertical pulling of vesicles adhered in a contact potential. For a range of applied forces, locally stable bound shapes, separated from the free shape by an energy barrier, can be found. The phase diagram contains regions with either a unique bound shape or an additional meta-stable shape. Upon pulling, these shapes unbind discontinuously since the vesicles disengage from the substrate while still possessing a finite adhesion area.read more
Citations
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Mechanical Properties of Pore-Spanning Lipid Bilayers Probed by Atomic Force Microscopy
Siegfried Steltenkamp,Martin Michael Müller,Markus Deserno,Christian Hennesthal,Claudia Steinem,Andreas Janshoff +5 more
TL;DR: The measured response depends in a known way on the system geometry (pore size, tip radius) and on material parameters (bending modulus, lateral tension), this opens the possibility to monitor local elastic properties of lipid membranes in a well-controlled setting.
Journal ArticleDOI
Endocytic proteins drive vesicle growth via instability in high membrane tension environment.
TL;DR: A protein-induced “snap-through instability” is revealed that offsets tension and drives vesicle growth during clathrin-mediated endocytosis, the main pathway for the transport of macromolecules into cells.
Journal ArticleDOI
Nano- and microparticles at fluid and biological interfaces.
TL;DR: This work discusses the interaction of single particles with interfaces and membranes, e.g. particles in external fields, non-spherical particles, and particles at curved interfaces, followed by interface-mediated interaction between two particles, many-particle interactions, interface and membrane curvature-induced phenomena, and applications.
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Boundary-value problems in the theory of lipid membranes
TL;DR: In this article, general contact conditions for lipid membranes interacting with curved substrates along their edges are developed for non-uniform adhesion between a bulk fluid or membrane and a rigid substrate.
Journal ArticleDOI
Adsorbed liposome deformation studied with quartz crystal microbalance
TL;DR: This work investigates the deformation of dimyristoyl phosphatidyl choline liposomes by quartz crystal microbalance (QCM) as a function of temperature and shows that it follows the dependence of this lipid's bending modulus on temperature, as expected from theoretical considerations.
References
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Weakly adhering vesicles in shear flow: Tanktreading and anomalous lift force
TL;DR: The deformation and unbinding of weakly adhering giant vesicles under hydrodynamic shear forces are reported and the lift force generated by the rotational flow in the vesicle was estimated to be at least two orders of magnitude larger than predicted by the simple theory.