Open AccessJournal Article
Effects of dietary supplementation with ethoxyquin, magnesium oxide, methionine hydroxy analog, and B vitamins on tansy ragwort (Senecio jacobaea) toxicosis in beef cattle.
Reads0
Chats0
TLDR
Dried tansy ragwort containing pyrrolizidine alkaloids was fed as 2.5% of a complete diet to Hereford steers, with and without (basal) a mixture of additives, suggesting some protective activity.Abstract:
Dried tansy ragwort containing pyrrolizidine alkaloids was fed as 2.5% of a complete (control) diet to Hereford steers, with and without (basal) a mixture of additives. The additives provided a dietary supplement equivalent to 0.1% ethoxyquin, 1% methionine hydroxy analog, 2% MgO, 2.7 mg of vitamin B6/kg of diet, 50 micrograms of vitamin B12/kg of diet, 0.45 g of folic acid/kg of diet, and 0.2 g of cobalt/kg of diet. The additives did not alter tansy ragwort toxicity substantially, as assessed by liver histologic changes, sulfobromophthalein clearance rate, and serum gamma-glutamyl transpeptidase activity. After 281 days, 1 of 4 steers fed the basal diet was alive, whereas 3 of 4 steers in the basal plus additives group were alive, suggesting some protective activity. The chronic lethal dose of tansy ragwort in steers was 3.6% of initial body weight.read more
Citations
More filters
Journal ArticleDOI
Toxicity and metabolism of pyrrolizidine alkaloids
TL;DR: Small herbivores such as sheep, goats, rabbits, guinea pigs and other herbivorous laboratory animals are highly resistant to PA toxicity, associated with a low rate of hepatic production of reactive metabolites (pyrroles) and a high rate of activity of detoxifying enzymes.
Book
A Guide to Plant Poisoning of Animals in North America
A. P. Knight,R. G. Walter +1 more
TL;DR: Plants that affect the skin and liver are considered together in this chapter because some plant toxins cause liver disease that results in secondary skin disease and the appearance of dermatitis and hair loss affecting the white-skinned areas.
Journal ArticleDOI
The toxicity of Senecio inaequidens DC.
Alberto Francisco Paulo Dimande,Christo J. Botha,Leon Prozesky,Lizette C. Bekker,G.M. Rosemann,Leonie Labuschagne,E. Retief +6 more
TL;DR: The toxicity of a plant implicated in an outbreak of poisoning of stock in Frankfort, Free State Province, South Africa was confirmed by confirming the presence of 4 different compounds, namely retrorsine and senecionine (known to be hepatotoxic) and 2 unidentified compounds.
Dissertation
Evaluation of endophyte-infected tall fescue products, their interaction with Senecio jacobaea in ruminants, and detoxification of alkaloids by ammoniation or ensiling after grinding
TL;DR: Evaluation of Endophyte-Infected Tall Fescue Products, their Interaction with Senecio jacobaea in Ruminants, and Detoxification of Alkaloids by Ammoniation or Ensiling after Grinding finds reduced performance is due to lowered FI and digestibility; while reduction in serum PRL isdue to the effects of EA on dopamine and its receptors which antagonize PRL secretion.
Journal ArticleDOI
Pyrrolizidinalkaloide und die Seneciose bei Tieren
TL;DR: In this article, a review of the Vergiftungssymptomatik is presented, in which the chronische Toxinaufnahme durch Verzehr kontaminierten Heus, the Seneciose des Pferdes is unheilbar.
Related Papers (5)
Effect of high-level copper feeding on the sulfur amino acid need of chicks fed corn-soybean meal and purified crystalline amino acid diets.
Kelly R. Robbins,David H. Baker +1 more