Journal ArticleDOI
Effects of dioxin exposure
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This article is published in The Lancet.The article was published on 1977-07-09. It has received 38 citations till now. The article focuses on the topics: Environmental exposure.read more
Citations
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Metastatic nonseminomatous germ cell tumors of the testis: results of elective and salvage surgery for patients with residual retroperitoneal masses.
Robert J. Nicholls,Robert Huddart,R. Sean Norman,Cyril Fisher,David P. Dearnaley,Alan Horwich,W. F. Hendry +6 more
TL;DR: A retrospective analysis was undertaken to define the outcome in these two groups of patients for retroperitoneal lymphadenectomy for metastatic, nonseminomatous germ cell tumor of the testis (NSGCT) and for patients who experience disease recurrence.
Journal ArticleDOI
Persistent hematologic and immunologic disturbances in 8-year-old Dutch children associated with perinatal dioxin exposure.
Gavin W ten Tusscher,P. A. Steerenberg,Henk van Loveren,Joseph G Vos,Albert E G K von dem Borne,Matthijs Westra,Johannes W van der Slikke,Kees Olie,Hendrik J Pluim,Janna G. Koppe +9 more
TL;DR: Signs of effects at the stem cell level of perinatal dioxin exposure, persisting until minimally 8 years after birth are provided, showing a decrease in allergy, persistently decreased thrombocytes, increasedThrombopoietin, and increased CD4+ T-helper and increasedCD45RA+ cell counts.
Journal ArticleDOI
Detection of the 2,3,7,8-tetpachlorodibenzo-p-dioxin (TCDD) receptor in rat liver by isoelectric focusing in polyacrylamide gels
TL;DR: A stereospecific, high-affinity binding protein (receptor protein) for 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD) in rat liver cytosol can be demonstrated using isoelectric focusing in polyacrylamide gels.
Journal ArticleDOI
Cancer immunotherapy based on recombinant Salmonella enterica serovar Typhimurium aroA strains secreting prostate-specific antigen and cholera toxin subunit B
Joachim Fensterle,Birgit Bergmann,C L R P Yone,Christian Hotz,Susanne R. Meyer,Simone Spreng,Werner Goebel,Ulf R. Rapp,Ivaylo Gentschev +8 more
TL;DR: The data demonstrate that a bacterial live vaccine encompassing T1SS in combination with cholera toxin subunit B can be successfully used for delivery of PSA to induce cytotoxic CD8+ T-cell responses resulting in an efficient prevention of tumor growth in mice.
Journal ArticleDOI
Ultrafiltration profiling and measurement of relative blood volume as strategies to reduce hemodialysis-related side effects.
TL;DR: UF profiles intermittently using high UF pulses cannot be recommended and a subgroup of patients at risk for hypovolemia-induced hypotension should be identified, and only these patients may benefit from blood volume-controlled UF.
References
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A health survey of workers in a 2,4-D and 2,4,5-T plan with special attention to chloracne, porphyria cutanea tarda, and psychologic parameters.
TL;DR: Severity of chloracne correlated significantly with the presence of hyperpigmentation, hirsutism, eye irritation, and a high score on the manic scale of the Minnesota Multiphasic Personality Inventory, but not with job location within the plant, duration of employment, or coproporphyrin excretion.
Journal ArticleDOI
Chloracne from the accidental production of tetrachlorodibenzodioxin.
TL;DR: A quick and reliable method of biological assay for the presence of dioxin in produced trichlorophenol was developed based on oral dosage to rabbits with assessment of liver function at fixed time intervals thereafter, which has already been superseded by instantaneous gas-liquid chromatography.