Effects of potassium, sodium, and azide on the ionic movements that accompany activity in frog nerves
Tomoaki Asano,W. P. Hurlbut +1 more
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TLDR
In desheathed preparations the magnitudes of the changes in ionic contents decreased as the concentration of the potassium in the bathing solution was increased, while changing the external sodium concentration produced small effects on the ionic shifts.Abstract:
Stimulation of intact or desheathed frog sciatic nerves produced an increase in the sodium content and a decrease in the potassium content of this tissue. In desheathed preparations the magnitudes of the changes in ionic contents decreased as the concentration of the potassium in the bathing solution was increased, while changing the external sodium concentration produced small effects on the ionic shifts. During tetanization, the rate of decline of the compound action potential also decreased as the external potassium concentration increased. Eliminating the activity respiration with 0.2 mM azide did not greatly modify the changes in sodium and potassium distribution that accompanied activity in either intact or desheathed nerves.read more
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Feasibility of developing a method of imaging neuronal activity in the human brain: a theoretical review.
TL;DR: It is proposed that, for the rapid changes related to the action potential, electron spin resonance using a potential-sensitive spin, label, impedance imaging and NMR are suitable in principle but that only ESR and impedance methods may have sufficient sensitivity and these merit further assessment.
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Further Studies on the Roles of Sodium and Potassium in the Generation of the Electro-Olfactogram Effects of mono-, di-, and trivalent cations
TL;DR: In the negative EOG-generating process a cation which can substitute for Na+ was sought among the monovalent ions, Li+, Rb+, Cs+, NH4 +, and TEA+, and the divalent ions and it was clarified that Na+ plays an irreplaceable role in the generation of thenegative EOG's.
Journal ArticleDOI
Metabolism of frog nerve during activity and recovery.
TL;DR: The amounts of ATP, ADP, CrP and lactate in single resting sciatic nerves are reported and compared with values given in the literature and the participation in the nerve metabolism of two enzyme systems, creatine phosphokinase and adenylate kinase, in interactions among some of these compounds is discussed.
Journal ArticleDOI
Potassium fluxes in desheathed frog sciatic nerve.
TL;DR: It is concluded that the active transports of K and of Na may be due to different processes, that an accumulation of K occurs only in exchange for an intracellular cation, which need not be Na, and that Na plays a specific, but unknown, role in K transport.
Journal ArticleDOI
Functional uptake of hydrazine by frog nerve in sodium-deficient Ringer's solution.
TL;DR: The relation between the HZ+ and the functional activity of nerve was further explored and it was found that among the onium ions tested, the hydrazinium ion (HZ+) could maintain the compound action potential of the frog sciatic nerve in a sodium-free Ringer's solution.
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