Electrophysiological Properties of the Canine Peripheral A-V Conducting System
TLDR
It was demonstrated that appropriately timed premature impulses could be confined within conducting tissue either proximal or distal to the area of maximum action potential duration.Abstract:
Action potential durations and local refractory periods were mapped along the course of canine conducting tissue from bundle branches to the termination of false tendons in ventricular muscle. Standard microelectrode techniques were used. Areas of maximum action potential duration, which coincided with areas of maximum local refractory periods, were consistently found 2 to 3 mm proximal to the termination of conducting fibers in muscle. The refractory periods at the areas of maximum action potential duration were quantitatively identical in the multiple false tendons of a segment of the conducting system, providing a uniform functional limit for the propagation of premature impulses across the distal end of the conducting system of the segments studied. It was demonstrated that appropriately timed premature impulses could be confined within conducting tissue either proximal or distal to the area of maximum action potential duration. This occurred when the area of maximum duration was still refractory, after other areas of the conducting system had recovered excitability. In most preparations, maximum action potential durations and functional refractory periods across distal false tendons were longer in tissue from the right side than from the left side of the conducting system.read more
Citations
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Functional properties of the left septal Purkinje network in premature activation of the ventricular conduction system
TL;DR: The result indicates that the Septal Purkinje network functions as the quickest pathway for conduction of premature impulses to the septal myocardium, and suggests that the functional properties of this fiber group contribute to the higher incidence of RBB block in ventricular aberrant conduction in supraventricular premature beats.
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Wei Ma,Feng-min Lu,Michael Shehata,Xunzhang Wang,Fan Zhang,Bingwei Chen,Dong-yan Wu,Le He,Shan Sun,Aijuan Cheng,Jun Ding,Hongliang Cong,Jing Xu +12 more
TL;DR: The HV interval and 12-lead ECG morphology of LPF-VT may help predict the successful site of origin and prove useful in guiding an effective ablation strategy.
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Characterization of the slowly inactivating sodium current INa2 in canine cardiac single Purkinje cells
Leonardo Bocchi,Mario Vassalle +1 more
TL;DR: INa2 is a sodium current that can be initiated after the inactivation of INa1 and has characteristics that are quite distinct from those of Ina1, which has a bearing on the mechanisms underlying the long plateau of Purkinje cell action potential and its modifications in different physiological and pathological conditions.
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Factors controlling impulse transmission with special reference to A-V conduction.
TL;DR: Various electrophysiologic as well as anatomic factors affecting impulse transmission in general, and A-V conduction in particular, have been discussed, to illustrate the complexity and diversity of the phenomenon of Conduction in the heart.
References
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Journal ArticleDOI
Temporal dispersion of recovery of excitability in atrium and ventricle as a function of heart rate.
TL;DR: It was concluded that spontaneous closely coupled beats occurring at slow ventricular rates in A-V dissociation may result from asynchrony in the repolarization of adjacent excitable units.
Journal ArticleDOI
Der Aktionsstrom der Myokardfaser im Sauerstoffmangel
TL;DR: In this paper, the Herzmuskel noch vom Skeletmnskel durch seine wesentlich größere Empfindlichkeit gegen Sauerstoffmangel.
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The action current of the myocardial fibers in oxygen deficiency
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