Journal ArticleDOI
Endocrine differentiation in mucoid carcinoma of the breast.
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TLDR
The relationship of this endocrine variant of mucoid carcinoma to other argyrophil carcinomas (so‐called ‘carcinoids’) of the breast is discussed and the salient pathological differences are detailed.Abstract:
Mucoid carcinoma of the breast is not a single homogeneous entity. It comprises two main variants separable on structural and cytological grounds and a smaller transitional type. The salient pathological differences are detailed. One variant is usually arygrophilic and contains dense core granules of the type seen in endocrine tumours. Both endocrine and amphicrine cells have been identified in this subtype. The relationship of this endocrine variant of mucoid carcinoma to other argyrophil carcinomas (so-called ‘carcinoids’) of the breast is discussed.read more
Citations
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Journal ArticleDOI
Refinement of breast cancer classification by molecular characterization of histological special types.
Britta Weigelt,Hugo M. Horlings,Bas Kreike,Malcolm Hayes,Michael Hauptmann,Lodewyk F. A. Wessels,D. De Jong,M.J. van de Vijver,L.J. van 't Veer,Johannes L. Peterse +9 more
TL;DR: The results imply that the correct classification of breast cancers of special histological type will allow a more accurate prognostication of breast cancer patients and facilitate the identification of optimal therapeutic strategies.
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A Brief Overview of the WHO Classification of Breast Tumors, 4th Edition, Focusing on Issues and Updates from the 3rd Edition
Hans-Peter Sinn,Hans Kreipe +1 more
TL;DR: This review of the WHO classification of Tumors of the Breast has focused on invasive carcinomas, precursor lesions, and some benign epithelial proliferations.
Journal ArticleDOI
A retrospective review with long term follow up of 11,400 cases of pure mucinous breast carcinoma
TL;DR: A large retrospective comparative analysis of Pure mucinous breast carcinoma cases with 20 years follow up confirms the less aggressive behavior of PMBC compared to IDC, and this favorable outcome is maintained after 20 years.
Journal ArticleDOI
Neuroendocrine differentiation in carcinomas of the breast: A study of 51 cases
TL;DR: The analysis of a consecutive series of 100 cases of breast cancer indicates that about 8% of breast carcinomas display some degree of NE differentiation, while the most frequent types of endocrine tumors (types A and C) have an intermediate grade of malignancy.
Journal ArticleDOI
Endocrine ductal carcinoma in situ (E-DCIS) of the breast: a form of low-grade DCIS with distinctive clinicopathologic and biologic characteristics.
William Y.W. Tsang,John K. Chan +1 more
TL;DR: E-DCIS is predominantly a disease of older women that is frequently accompanied by papillomas in the vicinity and may present as nipple discharge (an uncommon presentation in the usual forms of DCIS), but the pagetoid spread is a helpful clue to its neoplastic nature.
References
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Journal ArticleDOI
Invasive lobular carcinoma of the breast: incidence and variants.
V. Martinez,J. G. Azzopardi +1 more
TL;DR: In the diagnosis of problem cases, no single parameter proved reliable but a combination of several parameters enables one to make an objective diagnosis in about 95% of cases.
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Primary carcinoid tumor of the breast: A report of eight patients
TL;DR: The finding of intraductal carcinoma in three of three cases plus the identification by others of cells containing silver deposits in normal ducts of the breast, would suggest this anatomical structure as the possible site of origin of these tumors.
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Prognosis of mucinous (gelatinous) carcinoma of the breast.
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Grimelius' Silver Stain for Endocrine Cell Granules, as Shown by Electron Microscopy
TL;DR: Endocrine granules of pancreatic A cells, enter-ochromaffin and some nonenterochromaffin cells of the gastrointestinal mucosa, thyroid C cells and adrenal medullary cells were found to be selectively stained by silver grains 10-30 nm in diameter, either as a peripheral “halo” or covering the entire granule.
Journal ArticleDOI
Colloid carcinoma of the breast.
TL;DR: Although pure colloid carcinomas form a distinct category with an excellent prognosis, there is insufficient evidence that their treamtent should be more conservative than that for other infiltrative mammary carcinomas.