Enzymatic synthesis of dextran; acceptor specificity and chain initiation.
H. J. Koepsell,H. M. Tsuchiya,N. N. Hellman,A. Kazenko,C. A. Hoffman,E. S. Sharpe,R. W. Jackson +6 more
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This article is published in Journal of Biological Chemistry.The article was published on 1953-02-01 and is currently open access. It has received 203 citations till now. The article focuses on the topics: Dextran.read more
Citations
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Structure-Function Relationships of Glucansucrase and Fructansucrase Enzymes from Lactic Acid Bacteria
Sacha A. F. T. van Hijum,Slavko Kralj,Lukasz K. Ozimek,Lubbert Dijkhuizen,Ineke G. H. van Geel-Schutten +4 more
TL;DR: Emphasis now is on identification of residues and regions important for GS enzyme activity and product specificity (synthesis of α-glucans differing in glycosidic linkage type, degree and type of branching, glucan molecular mass, and solubility).
Journal ArticleDOI
Glucansucrases: mechanism of action and structure–function relationships
TL;DR: In order to synthesise oligosaccharides of biological interest or to develop vaccines against dental caries, elucidation of the factors determining the regiospecificity and the regioselectivity of glucansucrases is necessary.
Journal ArticleDOI
Synthesis of insoluble dextran and its significance in the formation of gelatinous deposits by plaque-forming streptococci
R.J. Gibbons,M. Nygaard +1 more
TL;DR: Polysaccharide fractions extracted from the deposits possessed a higher average molecular weight and relative viscosity than soluble polymers present in culture liquors, suggesting that molecular weight is important in governing their solubility.
Journal ArticleDOI
Homopolysaccharides from lactic acid bacteria
Pierre Monsan,Sophie Bozonnet,Cécile Albenne,Gilles Joucla,René-Marc Willemot,Magali Remaud-Simeon +5 more
TL;DR: The enzymatic synthesis of fructans (levan and inulin) is poorly documented at the molecular level, but the field of Streptococcus and Leuconostoc glucansucrases (glucosyltransferases and dextransucrase) has been well studied, both at the mechanistic and gene structure levels.
Journal ArticleDOI
Functional Oligosaccharides: Application and Manufacture
TL;DR: Oligosaccharides are attracting increasing interest as prebiotic functional food ingredients, although there is a need for more large-scale human trials using modern microbiological methods.
References
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Improved Techniques in Paper Chromatography of Carbohydrates
Journal ArticleDOI
The effect of certain cultural factors on production of dextransucrase by Leuconostoc mesenteroides.
TL;DR: Observation on factors affecting production of dextransucrase from Leuconostoc mesenteroides, strain NRRL B-512 and the possibility that more than one enzyme may be involved in the synthesis ofdextran is recognized.
Journal ArticleDOI
Enzymatic synthesis of dextran
H. J. Koepsell,H. M. Tsuchiya +1 more
TL;DR: A study of acceptor specificity in dextran synthesis was undertaken with the object of elucidating the polymerization mechanism and it was hoped that clues leading to the direct enzymatic synthesis of “clinical” dextransucrase with an average molecular weight in the range of 50,000 to 100,000 would be found.
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The mechanism of acceptor reactions of Leuconostoc mesenteroides B-512F dextransucrase.
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